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Unlocking the pathophysiological landscape of failing hearts: the importance of cell-enriched and histology-specific transcriptome mapping academic.oup.com/eurheartj/adva… #heart #failure #transcriptome #EHJ #Cardiotwitter @ESC_journals European Society of Cardiology

Proteomic Signatures for Risk Prediction of Atrial Fibrillation: Circulation 🥸 - we proposed to study this in the context of CAD/PCI but NHLBI reviewers did not like the idea: Michael Nanna Ajar Kochar 😱Summary 👇👇👇

Circulation Research May 23rd Issue is Out! Compendium on Interorgan Crosstalk in Heart Failure and Cardiometabolic Diseases In this issue read 14 reviews & 5 Research Letters: ahajrnls.org/4kaMnLo Gabriele G. Schiattarella Maria Kontaridis

New biomarker sub-study to the Phase III trial, FIGARO-DKD, shows that Finerenone modulates a multitude of circulating proteins. academic.oup.com/eurheartj/adva… #finerenone #cardiotwitter, European Society of Cardiology Journals, European Society of Cardiology

Wout has finished his masterpiece, he almost fell off his bike after pulling for Simon. CHAPEAU WOUT! #GirodItalia

🗞️ Insights into the European #heartfailure epidemiology European Society of Cardiology Journals Giuseppe Galati Amr Abdin Henry Han bit.ly/44665SJ

Healthspan has a proteomic signature! About 3,000 plasma proteins assessed and validated in 2 cohorts. Immune response and inflammation proteins stood out. pnas.org/doi/10.1073/pn…

Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of death worldwide. Yet, we lack circulating biomarkers for systemic atherosclerosis burden. Check out our new preprint describing the development of proteomic signatures or atherosclerosis👇

A noise-adapted AI algorithm using single-lead ECGs effectively predicted heart failure risk, showing improved performance over traditional risk scores. ja.ma/3ZUP4sa

Check out our new analysis Circulation: Genomic and Precision Medicine led w/ Min Seo Kim, MD, MSDH on an #ML-based proteomic score to predict future #afib ! Link + highlights below ⬇️ Mass General Heart Broad Institute Patrick Ellinor Akl Fahed

🧵1/📌 New insights from the FINEARTS-HF trial published in JAMA Cardiology: 💊 Finerenone shows consistent benefits in patients with HFmrEF & HFpEF — regardless of frailty status. #CardioTwitter #HeartFailure #Frailty #Finerenone #HFmrEF #HFpEF 2/ 👴 Frailty is common in HF

New online! Immunometabolism in heart failure nature.com/articles/s4156…

🗞️ Implantable cardioverter-defibrillators in ischaemic versus non-ischaemic heart failure: Insights from the #VICTORIA trial European Society of Cardiology Journals Giuseppe Galati Amr Abdin Henry Han bit.ly/4jZCuz5

Dealing with "third variables" in cardiovascular epidemiology - a review of the definitions of confounders, effect modifiers, and mediators, their interpretation, and the basic analytical tools for their investigation TIMI Study Group ahajournals.org/doi/full/10.11…

Immunomodulation for ARDS: Insights From Proteomics in COVID-19 Read the full research in the June issue of #journal_CHESTCritCare: hubs.la/Q03tFrqg0 #MedEd #JournalCHEST

At the age of 24, Werner Forssmann had a plan - to try the very first heart catheterisation on himself. Catheterisation is today a common procedure used to find heart defects, deliver medicine and open up blocked arteries. In 1956, Forssmann shared the medicine prize.

Natriuretic response prediction equation for use with oral diuretics in heart failure: read more in EHJ. doi.org/10.1093/eurhea… @ESCardio European Society of Cardiology Journals #HeartFailure #Diuretics #EHJ #CardiologyResearch

Big News! The 544th—and final—patient has been enrolled in #HIPEITHO, a landmark RCT comparing EKOS + anticoagulation vs. anticoagulation alone in intermediate-high risk #PE. Thank you to our investigators, The PERT Consortium® & Universitätsmedizin Mainz. Learn more: bit.ly/44VQapx

Self-Reactive B Cells in Artery Tertiary Lymphoid Organs Encode Pathogenic High Affinity Autoantibody in Atherosclerosis biorxiv.org/content/10.110…