Fantastic work from our friend and collaborator Karine Le Roch at UC Riverside. Culmination of her many years of work to fight against malaria! 👏👏

#RSGDREAM2024 concluding after two fun days talking about gene regulation, regulatory genomics. Thank you all for coming! Don't forget to fill the survey forms.gle/4vvTypQG4TBXoS… Your feedback is really important for us!

It was a 4days of great scientific discussion, brainstorming and some fun along the way! Big thanks to U.S. National Science Foundation for funding & NSF-NCEMS leaders & organizers for a well-organized summit! All that was left for us was to turn coffee into ideas and proto-proposals :) #NCEMSSummit

After many zoom meetings, discussions & learning from one another about different ways to look at the same data/problem, our perspective article on regulatory genomics is out. We have a “hallmarks of gene regulation” figure which i am planning to use in my talks. Enjoy reading!

Dear #academictwitter #sciencetwitter friends, i finally made the switch as my feed here is beyond recoverable and half of posts are from the owner guy. the sky is bluer on the other side and with starter packs you will connect with 100s of scientists in your field Find me there!

Extremely happy to share that our work DiffHiChIP: a method to identify differential chromatin interactions from HiChIP (and any other chromatin interaction data such as Hi-C, ChIA-PET), is now online. Preprint in: biorxiv.org/content/10.110…

I posted a longer description on bluesky if you want to learn more about this: bsky.app/profile/ferhat…

Happy to share Dante Bolzan’s delicious new preprint-Soffritto. He developed a deep learning model that accurately predicts high-resolution replication timing data (16-fraction) using commonly available data types Creative name by Dante but i stopped him from forcing an acronym😂

Our new paper is finally out, showing that the same enhancer sequences - and likely the same transcription factors recruited to them - affect the activity of distal enhancers and their looping over to target gene promoters. nature.com/articles/s4146…

Please also check out two other papers using HiChIP and Hi-C to detect genetic associations with chromatin looping by Ferhat Ay's and Gisela Orozco's labs, which were submitted in parallel to ours and provide complementary insights: nature.com/articles/s4146…

medrxiv.org/content/10.110…

Comparison of CD30L and OX40L Reveals CD30L as a Promising Therapeutic Target in Atopic Dermatitis. First author: Rinkesh K. Gupta; corresponding author: Michael Croft Read the article here: doi.org/10.1111/all.16… This study investigated whether targeting the T cell

Perspective on recent developments and challenges in regulatory and systems genomics academic.oup.com/bioinformatics… is out, amazing to think about this with Julia Zeitlinger (@[email protected]), Ferhat Ay, Shaun Mahony, Anthony Mathelier, Alejandra Medina-Rivera, Jason Ernst!

🧬 Just out in Bioinformatics Advances: "Perspective on recent developments and challenges in regulatory and systems genomics" Find the full paper here: doi.org/10.1093/bioadv… Authors include: Julia Zeitlinger (@[email protected]), Sushmita Roy @sroyyors.bsky.social,genomic.social, Ferhat Ay, Anthony Mathelier, Alejandra Medina-Rivera, Shaun Mahony,