🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

¡Vencer el cáncer es una Misión Posible! 💪🏼 🎥Descubre la nueva campaña protagonizada por investigadores e investigadoras del IRB Barcelona. 🧑🏼‍🔬👩🏾‍🔬 Vídeo completo ➡️bit.ly/MisionPosible_…

🪄Are you a Harry Potter fan? Do you love Xmas decorations? Then you are going to love our lab's themed door! ✨Check it out at the link and leave us a like! ❤️ instagram.com/p/CmEddotoXMW/…

🔥🔥🔥 Registrations open for the #BarcelonaBiomed Conference "Proximity-inducing Pharmacology: Targeted Protein Degradation & Beyond"! 22-24 May #TPD #chembio IRB Barcelona NO registration fee: run!!!🏃‍♀️🏃‍♀️ Short talks & posters An amazing lineup of speakers & chairs😍 👇👇

Glad to share our new review in ChemBioChem!! #Jake (biophysicist), #Carles (comput. chemist), & I delve into the crucial role of biophysical & structural data in TPD, highlighting the importance of efficient crosstalk with the plethora of new computational pipelines reported

✨Entering the 2nd year of PhD with poster presentation at #45sebbm_congress in Zaragoza. 👩‍🔬👨🏼‍🔬Together with my partners in crime Bárbara Barbosa Ferran José Duran No doubt that this is gonna be a good academic year🔥

Happy that this #chembio detective story is out at Angewandte Chemie!💊 🕵️‍♀️ We inform on synthetic lethal interactions to tackle #resistance to #degraders! Special congrats to @BarbMGBarbos Karen Sfyaki Ferran José Duran #Sergi!💜IRB Barcelona ▶️10.1002/ange.202316730 Thread 👇 (1/7)

Discovery and Mechanistic Elucidation of NQO1-Bioactivatable Small Molecules That Overcome Resistance to Degraders (Cristina Mayor-Ruiz and co-workers) Cris Mayor-Ruiz IRB Barcelona Bárbara Barbosa Karen Sfyaki onlinelibrary.wiley.com/doi/10.1002/an…

💊New drug reveals a key mechanism to overcome resistance to #ProteinDegraders. ✍️ Bárbara Barbosa Karen Sfyaki Ferran José Duran Sergi Rafael Cris Mayor-Ruiz URSAchem et al. 📰 Angewandte Chemie ➡️shorturl.at/gnFJY 📌doi.org/10.1002/anie.2… #IRBScience #TPD

🆕Chemical rewiring of ubiquitination by #degraders and their selectivity routes. ✍️Rory Whelan & Cris Mayor-Ruiz 📰🎂NatureStructMolBiol’s 3⃣0⃣th anniversary issue! 🔗shorturl.at/gmBIK 📌doi.org/10.1038/s41594… #IRBScience #TPD

📰Angewandte Chemie #OntheCover: "NQO1-Bioactivatable Small Molecules That Overcome Resistance to Degraders" ✍️Bárbara Barbosa Karen Sfyaki Ferran José Duran Sergi Rafael Cris Mayor-Ruiz URSAchem et al. 🔗shorturl.at/DFJO2 📌doi.org/10.1002/anie.2… #IRBScience #TPD 🧵👇

🚀Nace un programa pionero en Europa en #InvestigaciónTraslacional. 3⃣nuevos laboratorios mixtos del programa TRIP integran investigación biomédica fundamental y clínica con el objetivo de acelerar la llegada de resultados a pacientes. 🔗bit.ly/3P8Lpls #IRBScience

We are thrilled to share our new preprint around oncoprotein degradation in vivo —a fantastic collaboration with our friends in Salamanca Santamaria’s Lab Centro de Investigación del Cáncer/CSIC-USAL-FICUS! 😃 IRB Barcelona #TPD #KRAS 👇 biorxiv.org/content/10.110…

Mutations that stick: Unexpected discovery of molecular glue mimicry dlvr.it/TKDnhj