#AccessMicro is proud to launch our negative results collection, celebrating the best negative results studies published since the platform’s launch. Read the introductory editorial by Elisabeth Bik Elisabeth Bik and browse the collection: microb.io/4afpQIj #OpenScience

The labs of Christophe Zimmer @ImodLab and myself are looking for a technical assistant to join us full time at the @RVZ_Wuerzburg Universität Würzburg #UniWürzburg! Contact us if you want to help us decipher microbes and find antibiotics! More information can be found here: shorturl.at/quvB7

Leading PIs of our cluster of excellence Controlling Microbes to Fight Infections discuss the future of research on pathogens and commensals to fight infections: Why do some bacteria cause infections? Can ecological insights help to prevent bacterial infections? The Lancet Microbe thelancet.com/journals/lanmi…

ChimericFragments: computation, analysis and visualization of global RNA networks academic.oup.com/nargab/article…

Still few weeks to go! PhD and postdoc opportunities to study complex antibiotics response & phage defence. Join our lab! brochadolab.com/join-us

One more reason we need proteomics - to understand the impact of genetic diversity. The transcriptome alone does not provide a full enough pictures about gene expression differences. Great colleaboration with Joseph Schacherer 's team. More to follow soonish pnas.org/doi/10.1073/pn…

Why are infants susceptible to invasive pneumococcal diseases? Excited to share our latest work led by Kristen Lokken-Toyli which explores this question and elucidates the age-dependent mechanisms that drive pneumococcal spread from the mucosa. PLOS Pathogens journals.plos.org/plospathogens/…

At the Chair of Microbiology, we are looking for a coordinator to support the administration of two scientific consortia. Details below! Please, spread the information #JobAlert #academicjobs

Getting the band back together 😊

We found that anaerobiosis limits growth of Candida in the healthy gut, but disruption of anaerobiosis by antibiotics drives an intestinal bloom. Pharmacological restoration of anaerobiosis using drugs that stimulate epithelial oxygen consumption prevents this bloom.

Junior Research Group Leader with University of Würzburg - Come join us! Würzburg offers a fantastic collaborative and supportive environment with many outstanding scientists. Great place to start your independence - contact me if you have questions! nature.com/naturecareers/…

Want to study how fungal cells tweak their metabolism to become dug tolerant? Join us a postdoc in the ralser.group Charité - Universitätsmedizin Berlin in vibrant Berlin! tinyurl.com/4vtz2pj3

The lab is recruiting (postdoc level) 👇 Join us: we love good science and there is a great team spirit 💫 clavel.ukaachen.de; ukaachen.de/stellenangebot…

For 25 years, the Toll-like Receptor pathway was considered a series of distinct protein complexes that drive inflammation. Today, we report that the entire pathway, from receptor to transcription factor, is executed from within one complex—the myddosome. nature.com/articles/s4158…

Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model biorxiv.org/content/10.110…

Very pleased to see our interactive 3D visualization tool for bacterial single cell RNA-seq data in NAR Genomics and Bioinformatics -- great work from Max Seeger as part of his Master's in design at @THWS_Presse. Short video trailer showing it off here: youtube.com/watch?v=eoBJmH…

So happy to see our structural and molecular biology collaboration with Dr Sheena McGowan out in Communications Biology. We show that C. difficile uses an endolysin for toxin secretion, a mechanism which seems to occur in a controlled manner without cell lysis nature.com/articles/s4200…

Elucidating human gut microbiota interactions that robustly inhibit diverse Clostridioides difficile strains across different nutrient landscapes | Nature Communications nature.com/articles/s4146…

We determined gene essentiality in 13 Enterobacteriaceae including E. coli, Salmonella and Klebsiella strains, and find ~1/3 of the essential genome is variable -- but! there's no evidence for genus-specific essential genes, implying rapid turnover journals.asm.org/doi/10.1128/mb…

Shall we start calling them „asobiotics“? Probably easier than „antisense-based antibiotics“ or „antibacterial peptide-delivered antisense drugs“, to name just a few of the current names. To be discussed. Anyway, ASOBIOTICS 2024 was a big success. Big thanks to everyone involved.