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The Fe #Nitrogenase complex is solved ! New insights into a biocatalyst essential for life by producing bioavailable nitrogen: Dr. Johannes Rebelein's research team Johannes Rebelein, Frederik Schmidt, Luca Schulz has now uncovered the entire molecular structure: s.gwdg.de/NcUybG

Our manuscript is now online @Bioarchivepreprint! We explore the role of #ferredoxins (Fds) in nitrogen (N2) fixation via #nitrogenases (N2ases), the only enzymes to convert atmospheric N2 into bioavailable ammonia (NH3) and CO2 directly to hydrocarbons. dlvr.it/Szs2gs

Excited to share our work SYBORG out today in Nature Catalysis. A new synthetic CO2-fixation cycle, the THETA cycle, is designed, constructed in vitro, and modularly implemented in E. coli. Step by step, we are bringing synthetic CO2 fixation to life. nature.com/articles/s4192…

Ever wondered why #nitrene reactions are difficult to catalyze using #biocatalysis? Then check out our new publication in J. Am. Chem. Soc.! pubs.acs.org/doi/full/10.10…

Very excited to share my first corresponding & shared first author preprint (together with Clemens Böhm) about developing cell-free extracts from chloroplasts of different plant species for rapid prototyping to accelerate #plantsynbio in the chloroplast: biorxiv.org/content/10.110…

Paper Alert 🚀! Exciting findings from Johannes Rebelein! Two proteins are crucial for electron supply of Fe #Nitrogenase: new targets for improving #biocatalysis in #sustainable #fertilizer and carbon compound synthesis. Check out our press article: mpi-marburg.mpg.de/1361203/2024-0…

Happy and super excited to share our discovery of a protein fractal! We unravel the surprisingly simple emergence of these marvellous structures and show it might have even been an accident of evolution. Read the full story here nature.com/articles/s4158… Or just stick around 🧵

🌟An enzyme for carbon fixation🌟 Congratulations to Johannes Rebelein Max Planck Institute for Terrestrial Microbiology 🥳👏 He receives the #VAAMResearchAward 2024 at the #DGHMVAAM conference for his excellent work on a bacterial nitrogenase from Rhodobacter capsulatus that can convert CO2 to hydrocarbons🌞

Check it out📢 Latest research from Johannes Rebelein: Reshaping our understanding of nitrogenases, emphasizing their pivotal role in sustainable bioproduction. #sustainability #biotechnology #synbio #CO2fixation mpi-marburg.mpg.de/1422580/2024-0…

Paper Alert! Our findings on the iron nitrogenase’s ability to reduce #CO2 to feedstock chemicals under physiological conditions are out today Science Advances. Read the full story here: doi.org/10.1126/sciadv…

Grateful for receiving the PhD poster prize at last week´s Novo Nordisk Foundation Science Cluster conference on Dream Reactions of #CO2! Thanks to CORC_CO2 for organizing the event and Johannes Rebelein & IMPRS-μLife for all the support.

🌱C1 feedstocks (formate, methanol, etc.) are transforming #biomanufacturing. By using noncanonical redox cofactors (NCRCs) we can boost yields 📈 & unlock reactions that nature can't 🔓 🧵check our last publication Nikel SEM Group where we discuss how 👇1/n doi.org/10.1016/j.copb…

Our years of work on nitrogenase assembly paid off! So proud of this paper, which demonstrates the heterologous expression of an active nitrogenase. Thanks to everybody involved for a great team effort! Nature Catalysis, Ribbe Hu Labs, UCI Charlie Dunlop School of Biological Sciences, UCI Chemistry doi.org/10.1038/s41929…

Congratulations, Luca! 🥳well deserved! 👍👍mpi-marburg.mpg.de/1430229/2024-0…

Excited to finally making the first steps turning our DynaPore project into an actual technology! Please, support us by casting a vote for team DynaPore 🦖

Great work by @AnaLagoMaciel on the structural & biochemical characterization of methylthio-alkane reductase, a #nitrogenase-like enzyme that catalyzes carbon-sulfur bond cleavages for sulfur recycling. Check out Ana´s summary below!

We made it! 🚀 Our project "HAPPY" is a finalist for #HGP24! Our system for determining the age of yeast can replace animal testing and improve the efficiency of food and pharmaceutical production. 𝗣𝗹𝗲𝗮𝘀𝗲 𝘃𝗼𝘁𝗲 𝗳𝗼𝗿 𝘂𝘀 𝗻𝗼𝘄: hessischer-gruenderpreis.de/vote24#ig

New in @EMBOjournal, we studied the evolution of essentiality in Form I Rubisco. While Georg Hochberg nicely summarizes the evolutionary implications of our work, let me summarize some of the cool biochemistry surrounding it. doi.org/10.1038/s44318… 🧵

Paper alert! 🎉 Excited to share this collaboration from my PhD time @wethebarevenlab and SYBORG! We built a new bridge in central metabolism, connecting acetyl-CoA and pyruvate via a novel, engineered pathway. For some personal highlights, come along 🧵 nature.com/articles/s4146…

Happy to share our story on evolution of protein quaternary structure! We discover an astounding variation in assembly across evolutionary timescales contrasted by strong functional conservation suggesting a significant role of non-adaptive processes nature.com/articles/s4146… 👇🧵