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Meet Panacea, the toxin-busting goddess among antitoxins! Big thanks and congrats to all coauthors! pnas.org/content/119/6/… 🎉

It’s once again (tragically) time to strike, against constantly degrading working conditions and pay. Salary has fallen by avg 19% in real terms since 2009; how much worse is it going to get during a period of high inflation and cost of living crisis. #UCUstrike #OneOfUsAllOfUs

Please RT! The ulijaszlab.com is looking for 2 postdoctoral candidates to work on exciting NIH-funded microbiology projects: 1. Regulation of the S. pneumoniae capsule jobs.chronicle.com/job/445345/res… 2. Regulation of glyoxal toxicity in P. aeruginosa jobs.chronicle.com/job/445346/res…

Superbugs become vulnerable to antibiotics when their proteins fail to fold correctly. elifesciences.org/digests/57974/…

Reading the news coverage of the @UCU #FourFights strike, I get the impression that many people don’t know what University lecturers do (and why would they?), so here’s a thread on it. I’m a psychologist, so let’s start with the work of the average psychology lecturer. 🧵👇1/18

OUT NOW: ClpP inhibitors are produced by a widespread family of bacterial gene clusters By Gerry Wright & colleagues @GerryIIDR McMaster IIDR Beth Culp read it here: rdcu.be/cIGa0 nature.com/articles/s4156…

Something that is rarer than a sunny day in Ireland, a FULLY FUNDED PhD for INTERNATIONAL STUDENTS only, available with me here in Bristol Saving Cassava in Africa : A novel gene in a deadly virus findaphd.com/phds/project/s… please RT widely

In November, 2021 a group of B-lactamase experts met to reach a consensus on nomenclature and publication of alleles and enzyme variants. Consensus is now published journals.asm.org/doi/10.1128/aa… with a podcast asm.org/Podcasts/Edito… ASM Patricia Bradford

A quality control device for GroEL (Hsp60) ! check our new story revealing a novel aspect of this chaperone; great work @emile_dupuy Sander E. Van der Verren with Camille Goemans Han Remaut and many others biorxiv.org/content/10.110…

Breaking down complex ideas for curious readers, the TheScienceBreaker's latest story explores #AMR research about a strategy that could restore the effectiveness of a range of #antibiotics & drugs of last resort. Chris Furniss Nikol Despoina Mavridou UT Austin Stockholm University

Gracias juan luis ramos por el apoyo constante. Y gracias Antena 3 por mostrar la ciencia que hacemos en España y a la Fundación BBVA por financiarnos. Sin olvidar a nuestra colaboradora Blanca B. Landa por hacer posible este proyecto #Xylella #Pseudomonas

We are very excited to share the latest from the lab! In our paper published today in Nature Microbiology, we describe how outer membrane proteins in donor and recipient bacteria interact to mediate species specificity during bacterial conjugation nature.com/articles/s4156… 1/

Very happy to see this out in Microbiology Society as part of their review collection on Bacterial Cell Envelopes. I bet you have all heard about the TEM #betalactamase, but do you know how complex is the biogenesis of these #AMR proteins? Find our more here: microbiologyresearch.org/content/journa…

Proud to be an official depositor The National Collection of Type Cultures. Our E. coli K-12 strains expressing mobile colistin resistance (MCR) proteins are available there for anyone that needs to use them. #AMR journals.asm.org/doi/10.1128/mr…

📖This #OpenAccess review in #MicrobioJ provides a comprehensive overview of the journey of β-lactamases, published fee-free using #PublishAndRead Nikol Manasa Bharathwaj Chris Furniss Tracy Palmer Despoina Mavridou. doi.org/10.1099/mic.0.…

Super excited to share our latest preprint! We identified and characterized a novel regulator of the Lon protease. This protein, LarA, boosts Lon activity at the onset of proteotoxic stress when the cellular proteolysis demand is high. bioRxiv biorxiv.org/content/10.110…

New! Gram- cells need lipoproteins to build their surface. LolA & LolB deliver these in E.coli. But many species only have LolA - where's LolB? For Caulobacter, LolB is... LolA! It's a bifunctional protein! We can even tweak E.coli LolA to do double duty! pnas.org/doi/10.1073/pn…

Are you interested in #AMR, new #antibiotics, and the bacterial cell envelope? Our new (giant) review on how to use this external compartment to target bacteria is just out! With Nikol Ayesha Mahmood and Chris Furniss. Link: authors.elsevier.com/a/1hJrpEs76CODy

Very happy to see the final version of our LarA story published Nature Communications!! rdcu.be/drLOs Fantastic team effort by Deike Omnus, Matthias J. F., Aswathy Kallazhi, Maria X.Z. and our collaborators Michael Landreh & Axel Leppert!!! SciLifeLab Stockholm University

More than proud to see our work on SlyB out in press nature! Who would have thought a small membrane protein could form protective nanodiscs. A big thank you to all collaborators and reviewers. Find out more: nature.com/articles/s4158…