Read the full article here: meridian.allenpress.com/jgme/article/1…

Are you interested in mitochondrial biogenesis? Then check out the current issue of FEBS openbio with great contributions from Toni Barrientos, Agnieszka Chacinska, Nils Wiedemann, Jan Riemer and us. Feel the heartbeat! febs.onlinelibrary.wiley.com/toc/22115463/2…

Having the best time getting to hear about amazing science, clinical breakthroughs…and cuddling puppies at #AHA24 Scientific Sessions in Chicago 🐶♥️

Cell-type specific profiling of human entorhinal cortex at the onset of Alzheimer's disease neuropathology biorxiv.org/cgi/content/sh… #biorxiv_neursci

The first preprint of 2025! Together with @khorms, Vanja (Ivan Kulakovskiy), & our amazing team, we are excited to share PARADE: an AI framework for designing mRNA UTRs with enhanced cell-type specificity & stability. biorxiv.org/content/10.110…

A new study published in the New England Journal of Medicine Evidence & co-authored by Upstate's Dr. Ruth Weinstock has shown that automated insulin delivery systems can reduce the risk of hypoglycemia & hyperglycemia in older adults with type 1 diabetes. upstate.edu/news/articles/…

☕️Oborská-Oplová et al. report a conserved #mitochondria avoidance segment in the cytosolic ribosomal protein uS5 that prevents mistargeting of uS5 to the mitochondrial matrix and ensures cytosolic #ribosomal assembly. 👉rdcu.be/ecb32 bit.ly/3EZV8bi

Recently there is a study of Long Covid in China. Scientists utilized cryo-electron microscopy to examine myocardial biopsy tissue from long COVID patients and found severe damage to the mitochondria within the cells. This organelle impairment cannot be detected through routine

9 years ago today I asked a gynaecologist for a hysterectomy to stop the excruciating pain and she replied "what if you meet a man who wants children"

Taught my daughter’s science class about the thymus: how it looks huge at first & then “shrinks” But it’s a perspective trick because we actually grow around it Finally it really does regress but never quite vanishes Later: “Dad, the thymus is a metaphor for grief, right?”

Letting go isn't giving up; It's clearing space

Five different federal grants supported parts of this work to discover bacteriophages that specifically kill antibiotic resistant bacteria. They were all politically terminated three weeks ago.

This take from pilots via Dr. Glaucomflecken is fascinating:

New paper on mitochondrial distribution across the human body If you have more mitochondria than the average person in your heart, does that mean you also have more than average in your brain, muscles, kidneys, etc? We investigated inter-organ correlations in mitochondria 🧵

Absolutely crazy month for progress in the world of genome instability & DNA repair, especially as pertaining to aging. A few of the most exciting papers, a 🧵:

In the mitochondrial genome world, a preprint (by Sarah ! A friend) suggests many of the most canonical longevity signaling pathways are tied intrinsically to mitochondrial DNA stability. biorxiv.org/content/10.110…

In the category of "Not all heroes wear capes"... Dr. Peter Gates is an Australian neurologist who wrote the original 2005 paper on the Rule of 4s for localizing brainstem lesions. I first read this paper around 2012 while coaching med students. It was so helpful that I used it

The solution isn't to ban AI. It's to use it strategically. The choice is yours: Build cognitive debt and become an AI dependent. Or build cognitive strength and become an AI multiplier. The first brain scan study of AI users just showed us the stakes. Choose wisely.

I never thought I’d live in a world where people were opposed to heating milk to 165F for 15 seconds to kill disease-causing microbes because some podcast bro told them so…yet here we are. Poor Louis. He must be rolling in his grave. 2/

It is with heavy hearts that we share the passing of Dr. Samantha Garza. In honor of Sam's life, we invite you to donate in her memory to fund brain tumor research. Thank you to everyone who supported Sam throughout her battle. We love you forever, Sam. gofund.me/94b84c9b