🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Schizophrenia may be on the autism spectrum. 🧵1/10

🚨 Fellowship Alert! 🌍 We’re offering multiple fellowships for students & postdocs to attend #mbiosys25 in Chile! Don’t miss this chance to join key discussions in gene regulation & functional genomics. 📆 Apply by April 30! 🔗 molbiosystems.com

Baby genomics: newborn sequencing starts to fulfill its promise nature.com/articles/s4158…

Gracias por todo lo que nos entregaste a nosotros tus alumnos, Dra. Katia Gysling QEPD.

Microglia are such a pain. nature.com/articles/s4158…

Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease nature nature.com/articles/s4158…

Once you start enjoying delicious food, it’s tough to stop. Fascinating @ScienceMag study revealed that brainstem dopamine neurons activate during indulgent eating. Weight loss drug Ozempic temporarily suppresses these neurons, but their activity surges again in response to

Awesome work from Joachim De Jonghe - This is one of these cases when you experiment just works much better than any expectation -> Saturation genome editing of RNU4-2 reveals distinct dominant and recessive neurodevelopmental disorders medrxiv.org/content/10.110…

ZEB2 is a master switch controlling the tumor-associated macrophage program cell.com/cancer-cell/ab…

“Lo que dijo Kaiser sobre las vacunas es una burrada”, dice el doctor en biología Gabriel León. “Las vacunas no funcionan con metales pesados y no se fijan en el cuerpo. Esa frase tiene una intención, enturbia el ambiente con una declaración que está basada en mentiras”

1/ Matrix algebra felt abstract—until I applied it to biology. Now it's everywhere in my code, from RNAseq to proteomics. Let me show you.

5 tools to visualize genomic datasets 🧵 1. Karyoploter bernatgel.github.io/karyoploter_tu…

Protein codes promote selective subcellular compartmentalization | Science science.org/doi/10.1126/sc…

Introducing the world's first reasoning model in biology! 🧬 BioReason enables AI to reason about genomics like a biology expert. A thread 🧵:

Multiscale guidance of AlphaFold3 with heterogeneous cryo-EM data １．The paper introduces CryoBoltz, a novel method that combines cryo-EM density maps with pretrained protein structure prediction models, specifically AlphaFold3, to generate accurate atomic models of dynamic

Machine learning to predict de novo protein–protein interactions. #MachineLearning #PPI #ProteinInteractionDesign #MolecularSurfaces Trends in Biotechnology cell.com/trends/biotech…

Enhancers, how do they work (in vivo)? To find out, we mutagenized 7 human enhancers comprehensively in 12bp blocks and scored for activity in developing mouse embryos. rdcu.be/erD22 nature #mutagenesis #noncoding #enhancers

Today Arc Institute releases State, our first perturbation prediction AI model and an important step towards our goal of a virtual cell State is designed to learn how to shift cells between states (e.g. “diseased” to “healthy”) using drugs, cytokines, or genetic perturbations

Biology operates across multiple scales, from molecules and genes to cells, genomes, and clinical data. Understanding all of it needs models that think across every level at once. We are seeing now exciting multi-scale models that can help us scientists with these tasks ⬇️

A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function nature.com/articles/s4158…