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Pottier et al. identify a shared brain transcriptomic signature in TDP-43 type A FTLD patients with and without GRN mutations. bit.ly/3wpBL4e

Happy to be involved and make it happen! Excited for a great day and to connect in person once again #VIBpostdocday2022

Ending day 1 with the one and only Cyril shining bright at #ISFTD2022 🤩 Looking forward to what is still to come!

Day 2 of #ISFTD2022 and ready to present our large DNA methylation study in FTLD-TDP! Come see me at poster 91! RosaRademakersLab VIB Center for Molecular Neurology

📢 New paper alert! Our collaborative work on #TMEM106B pathology in the human brain 🧠

🏆Pierre Vanderhaeghen, Rosa Rademakers, and Ludo Van Den Bosch, the three consecutive winners of the Generet Award (Koning Boudewijnstichting), talk about the appeal and difficulties that come with studying rare diseases. 👉bit.ly/417hGOa

Happy to announce we are doing this again! Save the date and stay tuned for more info 📝 #VIBpostdocday2023

New paper alert 📣 In this study, we show that accumulation of TMEM106B fibrils in brain tissue is an age-dependent feature and modified by TMEM106B haplotype, potentially underlying its disease-modifying effect! Check it out in ⁦Brain⁩ 👇🏼 academic.oup.com/brain/advance-…

Day 2 of #Neuroepi23 and ready to present our large DNA methylation study in FTLD-TDP! Come see me at poster 34! RosaRademakersLab VIB Center for Molecular Neurology

What an incredible conference, filled with amazing talks and science, in gorgeous Mexico 🇲🇽✨🧬

Excited to share the latest paper out of the Arrant Lab! We compared lysosomal dysfunction between patients with FTD caused by progranulin mutations and patients with sporadic FTD with TDP-A pathology. Both patient groups had similar changes! actaneurocomms.biomedcentral.com/articles/10.11…

Postdoc Tingting Zhang's 2nd 1st-author publication in the same week! We showed that dysfunction of #dementia risk factor, #TMEM106B, in #microglia results in microglial survival defects in response to #demyelination. Many thanks to our collaborators! science.org/doi/10.1126/sc…

Do you work in biomedical #research? Do you also question your #antibodies? Dodgy antibodies waste time & $$$ + drive the reproducibility crisis. Let's talk about it! We've validated >50❗️Tau antibodies: rb.gy/jf247 Here's what we learnt & why it matters A 🧵 1/n

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This 👇🏼👏🏼👏🏼

Proud to be part of this amazing team 👩‍🔬 #endFTD

Milestone Alert🔔 Today marks the 500th experiment at our Single Cell Core since our launch on 1/1/22. Each cell holds a story, and today Melanie is the storyteller! 🏆🎂 Here's to the researchers, the cells, and the endless possibilities ahead! RosaRademakersLab VIB Technologies

Last chance to find out the results from our large DNA methylation study on FTLD-TDP patients! Come find me at poster #609 at #ADPD2024 🧠

Very happy and grateful to be one of the awardees this year! Much appreciated funds to dive deeper into the mechanisms of frontotemporal dementia with RosaRademakersLab at VIB Center for Molecular Neurology 🧠👩‍🔬🧬

🥳Congratulations to our 4⃣grantees! Thanks to Stichting Alzheimer Onderzoek, they can continue enhancing our understanding of neurodegenerative diseases: ▶️ Helen Ray-Jones from Valeriya Malysheva Lab ▶️ Cristina Vicente from RosaRademakersLab Lab ▶️ MINDlab ▶️ Sleegers Lab