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Delighted to try out the world’s first CRISPR-edited salad from Conscious Foods and Pairwise. Mustard greens were edited with Cpf1/Cas12a to reduce their spiciness while retaining their nutritional content (which is 2X better than romaine lettuce). 🙏 Feng Zhang for the invite

🧬 New-gen genome editors with potentially higher fidelity and capable of longer edits are here! Think prime editing but with DNA-dependent DNA polymerases instead of a RT. A comparison of recent tools from ErikSontheimerLab & Ben Kleinstiver Lab. Thread 🧵:

Our lab as well as students in the class I teach this semester enjoyed tasting the first CRISPR-edited salad greens, in which the myrosinase gene that results in the pungency of raw mustard greens (Brassica juncea) has been disabled, yielding a nutrient-dense, tasty, and

A GEFSES Student, Victoria Tenor, has become one of the finalists in the 2024 UCalgary 3MT Competition. Earlier, Mehtab Singh won the McGill Mac campus 3M competition. 3M Thesis presentation is one of the skill sets encouraged through GEFSES training. @NSERC_CRSN

FDA greenlights first test of gene editing therapy in babies from Jim Wilson startup iECURE. Read more in my story for Endpoints - endpts.com/fda-greenlight…

Scientists have developed an in vivo gene targeting system called pCriMGET_9-12a that may lead to the establishment of safer, more precise, versatile and efficient gene therapy methods in adult organs for the treatment of serious diseases. nature.com/articles/s4159…

GEFSES student Mehtab Singh, #HexaploidSingh, gave an excellent presentation on “SUSTAINABILITY THROUGH SCIENCE SYMPOSIUM.” McGill Macdonald Campus Plant Science McGill Jaswinder Singh NSERC / CRSNG Prairie Oat Growers Association

Upcoming Webinar! Dr. Jaswinder Singh will discuss some of the findings of the GEFSES_CREATE program. McGill Research + Innovation NSERC / CRSNG CropLife Canada

A new chapter for genome editing: RNA-guided recombinase enzymes have been discovered that enable the programmable insertion, inversion or deletion of long DNA sequences go.nature.com/3RHgWMA

The 2024 GEFSES Summer Workshop was a great way to reconvene great minds with a common interest in CRISPR-Cas-assisted agricultural development and environmental sustainability. We appreciate all the participants (in-person and online) and those who organized this workshop!

🌾 In Europe's first-ever field trial of gene-edited wheat, scientists have successfully reduced a potential carcinogen in wheat crops by using the #GeneEditing tool, #CRISPR! Knead to know more? 🍞 Visit: brnw.ch/21wMsIE

Research| RIKEN-IMS team developed a gene-editing technique for marmosets, modeling Alzheimer’s disease, using TALEN to introduce heterozygous exon skipping mutations. #GeneEditing Link: 👇 nature.com/articles/s4168…

* The CARBON Newsletter is back with the latest news on CRISPR in agriculture * In this edition you can read about a new optimised prime editing system for tomatoes, wheat with 97.7% reductions in gluten and much more. It's all availble for you from CRISPR Medicine News' website

Congratulations ! to Zhou for his first-author paper on metabolic engineering in oat Jaswinder Singh Lab Plant Biotechnology Journal McGill Macdonald Campus Plant Science McGill McGill Research + Innovation Oat Newsletter Dept. of Agriculture onlinelibrary.wiley.com/doi/full/10.11…

Exciting times ahead for wheat farming! 🌾🔬Canada’s first #GeneEdited wheat trial is set to be conducted this year, and may find ways to make our favourite grain even more resilient. See how this project will flour-ish at: brnw.ch/21wNXRY

📣Are you interested in gene editing 🧬 work in plants 🌱? Dr. Singh's Lab(Jaswinder Singh ) at McGill University has one Postdoctoral position open for application. See below for details 👇.

Daniel Getts and co-workers Myeloid Therapeutics present CRISPR-Enabled Autonomous Transposable Element (CREATE), a #genome editing system that combines #CRISPR/Cas9 with a modified LINE-1 retrotransposon machinery, for #RNA-based #gene editing and delivery. embopress.org/doi/full/10.10…