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Unraveling the influences of sequence and position on yeast uORF activity using massively parallel reporter systems and machine learning. biorxiv.org/cgi/content/sh… #bioRxiv

Happy RNA Day from the McManus lab! We’ve got strawberry pretzel gels, translating ribosome profiteroles, and of course GUAC! Coolest lab, coolest biomolecule! #RNADay #CMU

What does strength training have in common with working on a PhD? Read my article in ASBMB Today and find out! asbmb.org/asbmb-today/op…

biorxiv.org/content/10.110…

The paper from Tom Dever's lab and Green Lab showing Hox genes have much shorter UTRs (w/o IRESes) and conserved inhibitory uORFs is out! Congrats Ivaylo et al.! pnas.org/content/119/9/…

Check out our new manuscript demonstrating that conserved uORFs regulate HOX mRNA translation. A fun collaboration with Tom Dever’s lab at the NIH. Spicier than Frank’s red HOX sauce 😉 pnas.org/doi/10.1073/pn…

Barna Lab Please see the McManus Lab response to the Barna Lab's commentary drive.google.com/file/d/11PmIIZ… Our response covers the following key points:

Three months of lab hell in one Powerpoint slide.

I am so sick of universities talking about diversity and equity but not setting up robust, accessible systems to automatically pre-pay for trainee conference travel. This disproportionately affects URM and underprivileged students and needed to be fixed yesterday.

Our paper showing putative IRESes from #HOXA9 and other genes are false-positives is now published at #PNAS. Great #RNA and #RNAtranslation work by Christina Akirtava Christina and Gemma May Gemma May! pnas.org/doi/10.1073/pn…

Very excited for my upcoming talk! Thanks again for the invitation ☺️

Big fan of the DNA bake, syabira yusoff. I would like the recipe. Snack for lab meeting!

Thank you for publishing the recording! If you missed my talk and are interested in our work, here is a link! 🧬

iRNA_COSI Christina Fantastic ISCB webinar by Christina Christina! She explains in great detail how "IRESes" from Hoxa9 and ~ 100 other genes are false-positives, including some additional results not in the original paper (see the 21 minute mark). Congrats Christina!

My new podcast with ⁦The bae HQ⁩. How to adjust your perspective to become who you wanted to be, and my secrets on winning The Great British Bake Off 😉. #gbbo thebaehq.com/podcasts/episo…

Unraveling the influences of sequence and position on yeast uORF activity using massively parallel reporter systems and machine learning doi.org/10.7554/eLife.…

My book, Breaking Through, is out today! Join me on a deeply personal journey as I share my triumphs, failures, and discoveries that have revolutionized the field of mRNA. @crownpublishing penguinrandomhouse.com/books/706251/b…

Check out our most recent manuscript biorxiv.org/content/10.110…. Christina Akirtava (Christina) and Gemma May (Gemma May) tested > ten thousand natural yeast transcript leaders (5' UTRs) and determined the relative roles of RNA sequence motifs and structures. Nice work!

Delighted to share our recent manuscript on the roles of P-body factors in Candida albicans filamentation and stress response biorxiv.org/content/10.110… . Fantastic collaboration with Aaron Mitchell (UGA) and Fred Lanni (CMU), led by an amazing graduate student (Melissa Tosiano)!