Research Highlight by Lin Tang - An elegant mathematical model motivated by population genetics estimates total positive selection on observed and unobserved driver mutations in tissues by analyzing abundance and frequency of passenger mutations. nature.com/articles/s4159…

Do not miss out on the opportunity to publish your article ideas!💥 From discussions on fresh scientific debates to discursive writings about the weird and wonderful - all are welcome.😃🥳 Deadline for pitches is 13th February. Read the thread for more info. 👇👇👇

Come and join us! Whether you are computational yourself or just a secret admirer!

Great lightning talk at #EDxConf22 by Gladys Poon, PhD student in Early Cancer Institute, University of Cambridge Blundell Lab gladyspoon Jamie Blundell

Great Lightning Talk by PhD student gladyspoon from Cambridge! She identified clonal evolution using single-cell DNA sequencing. Check out her poster during networking session at #EDxConf22 Science and Innovation at Cancer Research UK OHSU Knight Cancer Institute

Spontaneous Reactions is back this Thursday 🥳 8pm at the Boathouse pub. This month, our guest scientist is computational oncologist Florian Markowetz (Florian Markowetz) from CRUK Cambridge Institute 🤩 Get your tickets at: eventbrite.com/e/spontaneous-…

Thanks to a complex mathematical algorithm, these plastic shapes follow a very specific route as they roll. In fact, researchers have shown that a shape can be designed to follow almost any path you can think of.

Last few places remaining for our Beginners Improv Course starting this Sunday (15th October). 8x 2 hour sessions lead by highly experienced improviser and all-round great guy Roni Jortner! £130. Contact [email protected] for info and to to sign up.

Having a great time at #EMBLCanGen this week! Grateful for the opportunity to present on my PhD work 👩‍🔬

Happy to share the updated version of our manuscript which now includes 80 single-cell derived phylogenetic trees from AML patients. We found that their statistical properties are representative outcomes of preleukemic evolution being driven by pervasive positive selection!

Delighted to share our latest work exploring levels of selection operating during pre-cancerous evolution usng single-cell DNA sequencing of HSCs led by the outstanding gladyspoon cell.com/cell-genomics/…

Happy to share our paper Jamie Blundell Aditi Vedi Mathijs Sanders where we use pre-AML single-cell phylogenies to measure evolutionary selection during the preleukemic human lifespan. Big thanks goes to Blundell lab as always! cell.com/cell-genomics/…

Very grateful to be given the chance to speak at CSHL conference - Probabilistic Modelling in Genomics 2025 on my latest work at HKU to understand cellular plasticity from mouse lineage tracing data! #probgen25 such a good conference for meeting people ☺️