George Ioannou (@gnioannou) 's Twitter Profile
George Ioannou

@gnioannou

Professor of Medicine, U. Washington | Director Hepatology| Physician-Scientist | Views= My own

ID: 1131011879197859840

calendar_today22-05-2019 01:40:19

2,2K Tweet

2,2K Followers

1,1K Following

Atul Gawande (@atul_gawande) 's Twitter Profile Photo

Nothing will kill more children than the ongoing decimation of CDC, NIH, and USAID work to lift vaccine uptake in the US and world. Child survival rose 75% in the last 50 years. Vaccines account for 40% of that. Measles vax alone was 60% of the benefit. thelancet.com/journals/lance…

Itai Yanai (@itaiyanai) 's Twitter Profile Photo

What Trump is doing is not reform, it is subversion.. The disruptions are already cascading through academia. Medical school have paused hiring; labs are considering when they'll have to let employees go; universities are curtailing Ph.D. programs.. Dhruv Khullar, The New Yorker

What Trump is doing is not reform, it is subversion..
The disruptions are already cascading through academia. Medical school have paused hiring; labs are considering when they'll have to let employees go; universities are curtailing Ph.D. programs.. <a href="/DhruvKhullar/">Dhruv Khullar</a>, The New Yorker
Stanford Div. of GI & Hepatology (@stanford_gi) 's Twitter Profile Photo

Stanford’s Division of Gastroenterology & Hepatology is recruiting a Division Chief! Join us in leading cutting-edge research, clinical excellence, and fellowship training! Help us share and spread the wrod!

Stanford’s Division of Gastroenterology &amp; Hepatology is recruiting a Division Chief! 
Join us in leading cutting-edge research, clinical excellence, and fellowship training!

 Help us share and spread the wrod!
Joseph Sleiman, MD, FACP (@josephhabibi_md) 's Twitter Profile Photo

#CGH4ALL 📣 🩺 NSBBs reduce first decompensation risk in cirrhosis w/ enduring CSPH 💥 Significant impact even in small GEVs and hepatitis C-cured patients! 👇 Read the full study from CGH 🔗 doi.org/10.1016/j.cgh.… Reported by Ariana Pereira Laura Turco Alessio Gerussi

#CGH4ALL 📣
🩺 NSBBs reduce first decompensation risk in cirrhosis w/ enduring CSPH
💥 Significant impact even in small GEVs and hepatitis C-cured patients!
👇 Read the full study from <a href="/AGA_CGH/">CGH</a>

🔗 doi.org/10.1016/j.cgh.…

Reported by <a href="/arianapg/">Ariana Pereira</a>

<a href="/Laura_Turco83/">Laura Turco</a> <a href="/AlessioGerussi/">Alessio Gerussi</a>
George Ioannou (@gnioannou) 's Twitter Profile Photo

1⃣Is MASLD associated with non-liver related mortality? 2⃣Is it *independently* associated with non-liver related mortality after adjusting for cardiometabolic factors? 3⃣Does MASLD *CAUSE* excess non-liver-related mortality? See Journal of Hepatology : authors.elsevier.com/a/1l6X6cOnAYPVk

1⃣Is MASLD associated with non-liver related mortality?
2⃣Is it *independently* associated with non-liver related mortality after adjusting for cardiometabolic factors?
3⃣Does MASLD *CAUSE* excess non-liver-related mortality?

See <a href="/JHepatology/">Journal of Hepatology</a> :

authors.elsevier.com/a/1l6X6cOnAYPVk
Luis Antonio Díaz, MD (@luisantoniodiaz) 's Twitter Profile Photo

🧬New 📋 Veeral Ajmera Journal of Hepatology: In MASLD, inherited genetic risk drives age-associated fibrosis. ⬆️ LSMs after 40y in high-risk genotypes 🧪 PNPLA3 genotyping may improve risk stratification 📈 Supports personalized medicine 🔗 doi.org/10.1016/j.jhep… Rohit Loomba UCSD Gastroenterology

🧬New 📋 <a href="/AjmeraVeeral/">Veeral Ajmera</a> <a href="/JHepatology/">Journal of Hepatology</a>: In MASLD, inherited genetic risk drives age-associated fibrosis.

⬆️ LSMs after 40y in high-risk genotypes
🧪 PNPLA3 genotyping may improve risk stratification
📈 Supports personalized medicine
🔗 doi.org/10.1016/j.jhep…
<a href="/DrLoomba/">Rohit Loomba</a> <a href="/UCSD_GI/">UCSD Gastroenterology</a>
Scott Isaacs (@scottisaacsmd) 's Twitter Profile Photo

Thrilled to announce the release of the new American Diabetes Association - DiabetesPro Consensus Statement: #MASLD is now recognized as a major metabolic complication in type 2 diabetes and obesity, underscoring the central role of insulin resistance and cardiometabolic risk factors in its pathogenesis.

Thrilled to announce the release of the new <a href="/ADA_DiabetesPro/">American Diabetes Association - DiabetesPro</a> Consensus Statement: #MASLD is now recognized as a major metabolic complication in type 2 diabetes and obesity, underscoring the central role of insulin resistance and cardiometabolic risk factors in its pathogenesis.
George Ioannou (@gnioannou) 's Twitter Profile Photo

If AFP level was 1-3 the last few times it was measured, & then "jumps" to 9, this should be a *POSITIVE* screening test for HCC (even if 9 is not above threshold): 👉Serial AFPs improve HCC screening sensitivity compared to fixed threshold journals.lww.com/hepcomm/fullte…

If AFP level was 1-3 the last few times it was measured, &amp; then "jumps" to 9, this should be a *POSITIVE* screening test for HCC (even if 9 is not above threshold):

👉Serial AFPs improve HCC screening sensitivity compared to fixed threshold

journals.lww.com/hepcomm/fullte…
George Ioannou (@gnioannou) 's Twitter Profile Photo

🙏🙏Norah Terrault🙏🙏 For best HBV lecture: 1️⃣Functional Cure= Loss of HBsAg 2️⃣Loss of HBsAg means loss of “integrants” (HBV integrated in human genome) 3️⃣Robust pipeline of drugs for functional cure ➡️ Bepirovirsen first

🙏🙏Norah Terrault🙏🙏
For best HBV lecture:
1️⃣Functional Cure= Loss of HBsAg
2️⃣Loss of HBsAg means loss of “integrants” (HBV integrated in human genome)
3️⃣Robust pipeline of drugs for functional cure ➡️ Bepirovirsen first
Kristin M. Collier, MD (@hsrdirector) 's Twitter Profile Photo

I ran a workshop today —“Is Medicine a Spiritual Practice?” We read this piece. “Illness is a spiritual event. Illness grasps persons by the soul and by the body & disturbs them both. Illness raises questions about meaning, value & relationship. These are spiritual questions.”

I ran a workshop today —“Is Medicine a Spiritual Practice?”

We read this piece.

“Illness is a spiritual event. Illness grasps persons by the soul and by the body &amp; disturbs them both. Illness raises questions about meaning, value &amp; relationship. These are spiritual questions.”
Elliot Tapper (@ebtapper) 's Twitter Profile Photo

Pickle juice for muscle cramps is back in the news because of Carlos Alcaraz winning Roland Garros For anyone interested in knowing why this works and the evidence for it, you can find it in these articles Review: pmc.ncbi.nlm.nih.gov/articles/PMC10… Clinical trial: pmc.ncbi.nlm.nih.gov/articles/PMC11…

Hepatology Communications (@hepcommjournal) 's Twitter Profile Photo

✅ out this month’s issue‼️ Learn about:  📑 Role of muscle in MASLD❓ 📑 Optimal AFP cut-off in HCC screening in cured HCV?❓ 📑 Min meaningful diff in PROs in cirrhosis❓ 📑 How well are we treating itch in PSC❓ 📑 How best to 🔍 fibrosis in MetALD❓ journals.lww.com/hepcomm/pages/…

✅ out this month’s issue‼️
Learn about: 
📑 Role of muscle in MASLD❓
📑 Optimal AFP cut-off in HCC screening in cured HCV?❓
📑 Min meaningful diff in PROs in cirrhosis❓
📑 How well are we treating itch in PSC❓
📑 How best to 🔍 fibrosis in MetALD❓
journals.lww.com/hepcomm/pages/…
Journal of Hepatology (@jhepatology) 's Twitter Profile Photo

📢Our new Impact Factor is 33.0🎉 🥇Ranking number 1 in the Hepatology field once again! 👏Thanks to the Editorial Team, untiring peer reviewers & very innovative authors❕ EASLnews EASL Education #LiverTwitter

📢Our new Impact Factor is 33.0🎉

🥇Ranking number 1 in the Hepatology field once again!

👏Thanks to the Editorial Team, untiring peer reviewers &amp; very innovative authors❕

<a href="/EASLnews/">EASLnews</a>
<a href="/EASLedu/">EASL Education</a>
#LiverTwitter
Gordon H. Guyatt (@guyattgh) 's Twitter Profile Photo

Brian Haynes, PJ Devereux and I present the rationale behind the third key principle of #EBM: evidence alone never is sufficient for decisions, #patient values and preferences always crucial. Or as this #BMJ article put it, evidence doesn’t make decisions, people do.

eleni chrysostomides (@elenichrysos) 's Twitter Profile Photo

Ειλικρινή συλλυπητήρια στον George Ioannou , Constantinos Ioannou και σε όλη την οικογένεια, για τη μεγάλη τους απώλεια. Μετά την εκδημία των ανδρών επιφανών, όπως ήταν ο μ. Ιατρός Νίκος Γ. Ιωάννου, μένει η αγαθή μνήμη, το έργο και η προσφορά προς την πατρίδα. Με μια λέξη, μένει η υστεροφημία.

Ειλικρινή συλλυπητήρια στον <a href="/gnioannou/">George Ioannou</a> , <a href="/K_Ioannou/">Constantinos Ioannou</a> και σε όλη την οικογένεια, για τη μεγάλη τους απώλεια. Μετά την εκδημία των ανδρών επιφανών, όπως ήταν ο μ. Ιατρός Νίκος Γ. Ιωάννου, μένει η αγαθή μνήμη, το έργο και η προσφορά προς την πατρίδα. Με μια λέξη, μένει η υστεροφημία.
George Ioannou (@gnioannou) 's Twitter Profile Photo

Use Fibroscan liver stiffness + platelet count to document: ➡Clinically Significant Portal Hypertension (CSPH) ➡compensated Advanced Chronic Liver Disease (cACLD) Our Hepatology📰 shows the categories & rationale & argues for category of "critical" CSPH journals.lww.com/hep/fulltext/2…

Use Fibroscan liver stiffness + platelet count to document:
➡Clinically Significant Portal Hypertension (CSPH)
➡compensated Advanced Chronic Liver Disease (cACLD)
Our Hepatology📰 shows the categories &amp; rationale &amp; argues for category of "critical" CSPH
journals.lww.com/hep/fulltext/2…
Anil Makam (@anilmakam) 's Twitter Profile Photo

Agree. True in medicine too. Notes are cognitive. If it's not then you're doing it wrong. Also why metrics that study EHR time as a waste are misguided. This too often includes cognitive time. Unless we dont want doctors to think and just do