Knight Lab (UC San Diego School of Medicine / UCSD Engineering) is excited to announce a new release of Greengenes in Nature Biotechnology (nature.com/articles/s4158…). With this release, we provide a single taxonomy and phylogeny unifying 16S and shotgun metagenomic analyses! A thread (1/n)

Today we report a detailed map of interactions between the immune system and the gut microbiome. Kazuki Nagashima led the charge w/ help from Aishan Zhao and Kat Atabakhsh. nature 1/40 nature.com/articles/s4158…

One man's niche is another man's treasure 😀

.Yi Yang & Cadwell Lab discuss work from Dr. Hiutung Chu 朱曉彤 @chulab.bsky.social (bit.ly/3v1Yh5k) revealing that commensal bacteria elicit tonic type I interferons to prime dendritic cells and induce regulatory T cells that maintain a tolerogenic intestinal milieu. bit.ly/3RonjDu

OUR LATEST ARTICLE HAS BEEN PUBLISHED 🎉 Read our study ‘Antibiotic Use in the 12 months Prior to Ileal Pouch-Anal Anastomosis Increases the Risk for Pouchitis’ here ➡️ pubmed.ncbi.nlm.nih.gov/38556033/ Edward Barnes MD MPH Karachalia Sandri Anastasia #HansHerfarth Tine Jess Danmarks Grundforskningsfond Aalborg Universitet

Microbiota therapeutics for inflammatory bowel disease: the way forwar... sciencedirect.com/science/articl…

How to pick a problem. Today in Cell. 1/53 cell.com/cell/fulltext/…

We have enrolled the first patient in the pivotal Phase 3 study of VE303 for the prevention of recurrent C. difficile Infection. To our knowledge, this is the 1st registrational study of a Live Biotherapeutic Product for rCDI An important milestone in our field /1

⌛️Starting in 10 minutes! 🤩Learn about cardiovascular risk assessment in IBD from the world expert Edward Loftus 🔗Not yet signed up? bit.ly/Global-IBD-VP-… ✅Summary incoming🧵 Miguel Regueiro Stefan Holubar MD MS David Liska Scott R. Steele Fernando Gomollón Y-ECCO iris dotan

Every year, Jean-Frederic Colombel hosts the GI Division #IBD Retreat to address challenging topics in #IBD. We're proud to keep the tradition going this year at IBD Retreat 2024! Register here to join: form.jotform.com/kalish39/IBDre…

Wow, @nature has retracted the 2020 Poore et al. cancer microbiome paper that we showed (journals.asm.org/doi/10.1128/mb…) was deeply flawed. The retraction date is tomorrow so I can't yet read the official notice, but I'll update when I can Retraction Watch Professor Booty PhD

Out now 🚨 in Gastroenterology is your latest update on selective IL-23p19 inhibition in IBD! Amongst other topics featuring discussion of pathogenesis, PD/PK, efficacy, safety, positioning, and more! Together with Jean-Frederic Colombel Mehandru Lab @MountSinai & Ryan Ungaro MD MS gastrojournal.org/article/S0016-…

Sir Patrick Vallance KCB has been appointed Minister of State (Minister for Science) in the Department for Science, Innovation and Technology Department for Science, Innovation and Technology.

A scientist. As minister for science. Shouldn't be surprising or notable, but this heartens me as much as anything else i have seen in the last 24 hrs (speaking as someone who grew up in Liz Truss’s former constituency). 🇬🇧

Trafficking circuit of CD8+ T cells between the intestine and bone marrow governs antitumour immunity | Nature Cell Biology Yet another example of gut immune-imprinting for functions beyond the gut #InGutWeTrust nature.com/articles/s4155…

Age-related patterns of microbial dysbiosis in multiplex #IBD families 🔖 The BMJ 👥Jacobs Lab Elizabeth A Spencer MD MS Graham Britton Joana Torres Jean-Frederic Colombel Jeremiah Faith Marla Dubinsky et al gut.bmj.com/content/early/…

We were very sorry to learn of the death this week of our friend and colleague Prof. David Stephens. As a scientist and educator David touched the lives of countless biochemists and cell biologists, and he will be fondly remembered. Our thoughts are with his family and friends.

This is very sad news. David's was the first lab I ever worked in and I learnt so much from him during that time. Thinking of his family and everyone Bristol Biochemistry

What #diet should we recommend in #CD? We show ⬆️fiber ⬇️fat diet improves metabolic fcn of the #microbiomeIBD in colonic > ileal CD but < than healthy peeps ⁦Helmsley Charitable Trust⁩ ⁦Bambino Gesù⁩ ⁦Oriana M. Damas, MD MSCTI⁩ Jessica R Allegretti⁩ ⁦Kelly Issokson MS RD CSDH LDN CNSC (she/her)⁩ microbiomejournal.biomedcentral.com/articles/10.11…

New research from Mehandru Lab @MountSinai describes the depletion of germinal center B cells and IgA+ plasma cells in the #GI tracts of people living with #HIV. @francescacossa1 Read more in Science #Immunology: bit.ly/3Yd0Uwg