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SARS-CoV-2 Testing Strategies for Outbreak Mitigation in Vaccinated Populations medrxiv.org/cgi/content/sh… #medRxiv

Exciting work from an amazing Princeton undergraduate from our lab!! SARS-CoV-2 Testing Strategies for Outbreak Mitigation in Vaccinated Populations medrxiv.org/content/10.110…

Excited to share a new manuscript! Deep nets are great at predicting visual neurons. Yet, they are unable to tell us which artificial neuron directly corresponds to a biological neuron… until now! biorxiv.org/content/10.110… (yes, that is indeed a fictive female fly, good guess!)

Why would fast-growing cells switch to aerobic glycolysis even when respiration generates more ATP? Enzyme cost? Check out our new preprint - Respiration produces ATP faster with less enzyme. Aerobic glycolysis primes yeast’s proteome for oxygen limitation biorxiv.org/content/10.110…

Excited to share our work online at Cell today. Isotope tracing into bacterial-specific protein sequences tells what nutrient different microbes prefer in the gut. Huge thanks to Josh, Cholsoon Jang, Martin Wühr, Mohamed Donia for the guidance. cell.com/cell/fulltext/…

Looking forward to visiting the department!

📢Thrilled to share -re-print alert from Laboratory of Interfaces, Flow and Electrokinetics. Led by Ben Alessio "Diffusiophoresis-enhanced Turing Patterns". Comparison of fish patterns with and without diffusiophoresis (pc credits to Birch Aquarium for the Ornate Boxfish and craigjhowe for the Jewel Moray Eel).

Thrilled to share our study with Z. Gitai, N. Wingreen & T. Silhavy. We measured degradation of ~3.2k E. coli proteins in various conditions, finding cytoplasmic proteins recycle under nitrogen-limitation. biorxiv.org/content/10.110… #Proteomics #ProteinTurnover #EcoliResearch

I’m thrilled to announce that I will be joining BioE department at UPenn Penn Bioengineering as an assistant professor, starting Jan 2024! My future lab is gonna have fun imaging and modeling metabolism!

Fantastic piece of work! Congratulations Yogesh!

Yogesh has been an amazing mentor and friend throughout my scientific journey and has gone above and beyond to support me on multiple occasions. Would highly recommend the lab for its amazing Science, supportive environment and a productive career.

🎉 Excited to share a big part of my PhD work in Allon Klein Lab that took many, many years and my blood, sweat, and tears! 😅 We ask - What’s the role of cell division in the formation of initial cell types during early development ?🧐 biorxiv.org/content/10.110… 🧵 (1/14)

Sayantan Dutta, Ashesh Ghosh, Alistair Boettiger, and Andy Spakowitz published "Leveraging polymer modeling to reconstruct chromatin connectivity from live images" in Biophysical Journal. Excellent work, Sayantan and team! cell.com/biophysj/pdf/S…

Shen Lab website is up! We will be open in Jan 2024 Penn Bioengineering 🥳 Come join us if you are interested in imaging and metabolism🔬 Pls retweet imaging-systems-metabolism-lab.com

Yihui has been an amazing mentor. Would join her lab in a heartbeat!

Excited to share my postdoc work out in Nature Chemical Biology! We explored the preferences and efficiencies of ATP pathways in cells and tissues. By quantifying metabolic flux and proteomics, we found that respiration makes ATP faster per enzyme mass than glycolysis🧵nature.com/articles/s4158…

Thrilled to share our approach for language model-guided discovery of unknown mammalian metabolites: DeepMet. We’ve now used this approach to discover ~50 new human and mouse metabolites! biorxiv.org/content/10.110…

Thrilled to share that my main postdoctoral project in Josh Rabinowitz’s lab is out today at Cell! We found an unexpected, diet- and microbiota-dependent mechanism that affects the anticancer activity of PI3K inhibitors. Thread below👇

Right on time for #ASMS2025 #SpatialMetabolomics Imaging MS Society "Spatial metabolic gradients in the liver and small intestine" - Congratulation to Laith and team biorxiv.org/content/10.110…