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This is incredible work! Recruiting to an RCT in busy EDs requires so much input from so many people and I'm so impressed that we've got so many in such a short period of time.

Cool; but we have to be super skeptical of these small single centre RCTs where there is no real clear plausible causal mechanism and a HUGE effect (larger/similar to abx). Empirical evidence would suggest repeat studies will be null.

This is really cool and shows the power of large scale WES data in overturning long held conclusions

Delighted to have the opportunity to present to the NIHR strategy board on Birmingham’s leading pancreatic cancer trial portfolio with infant in tow (inset day equals daddy day care).

Excited to announce that we randomised our first patient into the #ROADMAPtrial today! First of thousands, answering important questions in prosthetic joint infection. See roadmaptrial.com for more deets. #IDXposts #PJI

this remains probably the best thing that ever happened to me

It is totally weird that we seem to be sleepwalking into a situation where doctors are unable to get docs. Numerous stories locally of insane competition (80:1!) for jobs that 5 years ago would have had 1-2 candidates. Why is this?

It is insane how people get away with this. It is incumbent on the team getting the referral to take it. Of course, some referrals don't contain enough information but now most places have access to GP records you can look up the info yourself. Waste of GPs time.

Starting to think I might not have the CV for this job

Our sites have been keeping us busy! We have 49 participants enrolled in just over 5 weeks! And we have new sites to welcome to the team: Research at Leicester's Hospitals Royal Berkshire NHS Foundation Trust University Hospitals Bristol and Weston NHS FT all received greenlight! 🙌🟢

Gunnar from EUCAST talking about how oxacillin discs have a complex relationship with penicillin MICs in S pneumoniae #escm

It is incredible that 3/4 presenters in the bacteraemia session at ECCMID are from Melbourne. Best place in the world to do bacteraemia research.

I have taken three (3) GWR trains today, and every single one has been on time, quiet trains, everyone polite, and I even got an Easter egg gift from GWR. And I was in Vienna yesterday on a (very) delayed train! Maybe we are too mean on British trains...

Incredibly important work. I suspect VAC use will still continue...

Dear GP, Please do the needful UKHSA (Do they realise this might be *quite* a lot of work for GPs..?)

I don't doubt this story at all - but interestingly I have never had anything like this personal experience. Nursing staff (and AHPs) generally very respectful and hard working. I think some hospital cultures clearly very different from others.

There is so so so so much of this in medicine. And each individual cost small enough that it seems bearable. But total cost huge.

Not a domain expert but never had to sign a code of conduct before agreeing to participate in a conference (or not one so explicitly banning certain topics). Certainly seems odd from the outside...

We did it! Absolutely thrilled to share the results of the ASPEN trial published today in NEJM Brensocatib(10mg and 25mg vs placebo) reduced exacerbations over 52 weeks and slowed lung function decline A new treatment for bronchiectasis patients nej.md/4lBHwUr

Earlier this week, we deployed ~12.99 pounds of sulfur dioxide (SO₂) into the stratosphere, including one launch that reached an altitude of 101,400 feet. These deployments offset the warming effect of 5,895 metric tons of CO₂ for a year. In under three hours, we achieved the