Most happy to see Hillary Elrick on stage presenting the group's work on Oxford Nanopore data analysis, including her new tool #SAVANA for SV calling in cancer genomes! Way to go, Hillary! The 'group' in this context includes all our great collaborators Michael Hubank Andrew Beggs @me_tanguy &more!

Long-read genome sequencing is Nature Methods' method of the year & a technology driving our understanding of cancer. Isidro Cortes-Ciriano’s group & collaborators are exploring new applications & developing new analysis tools in this space. ebi.ac.uk/about/news/per… #WorldCancerDay

Mark you calendars! Next Cambridge Computational Oncology Meeting is May 5 at the EBI in Hinxton. Speakers: Hillary Elrick Hillary Elrick , Alex Gutteridge Alex Gutteridge and Peter Campbell

We (Isidro Cortes-Ciriano) wrote a small R package to quickly visualize (complex) rearrangements and copy number. Please try it and feedback always welcome! biorxiv.org/content/10.110…

Had a blast the last three days on the nf-core Nextflow Hackathon at the Wellcome Genome Campus . Special thanks to the organizers @SangerToL EMBL-EBI and my awesome co-hackers Carolin Sauer Hillary Elrick mariakalyva fmuyas . Pics by @SangerToL

Join us on May 5th EMBL-EBI for an afternoon of great talks and coffee/tea/cookies. Tell your colleagues and bring a poster! If you are not from campus please register here so that you can get through security effectively. docs.google.com/forms/d/e/1FAI….

Glad to have contributed to this fantastic cancer biology story on shattered chromosomes, driven by the Peter Ly and Isidro Cortes-Ciriano, out today in nature EMBL-EBI nature.com/articles/s4158…

Attending Oxford Nanopore London Calling 2023? Don't miss the talks from our lab: Hillary Elrick on our somatic SV caller #SAVANA (teaser: she will show mind-blowing examples of complex somatic rearrangements in clinical samples), and Carolin Sauer on cfDNA analysis! #NanoporeConf EMBL-EBI

Very proud to introduce you SComatic (Nature Biotechnology ): a breakthrough method for detecting somatic mutations in single-cell datasets without using a reference sample. Amazing work carried out with the huge support of Isidro Cortes-Ciriano and all co-authors! EMBL-EBI EMBL

Join us once more for an excellent meeting and feel free to bring a poster!

We will be recruiting a PhD student this year! Apply to join us (mariakalyva Hillary Elrick fmuyas @Jaesvi42 Carolin Sauer and others not on Twitter) at EMBL-EBI ! Application details below 👇

📢We are recruiting! embl.org/jobs/position/… Come join us at EMBL-EBI! Exciting Cancer Research UK-funded project focused on long-read sequencing data analysis and early cancer detection. Ideal position to train in basic and translational research working w us Andrew Beggs Michael Hubank & others!

The Cambridge crew are here in sunny Faro, Portugal, ready to learn and meet new connections at the #CCESumSchool23! 👨‍🎓👩‍🎓🏫🧬🔬👩‍⚕️👨‍⚕️👩‍🔬👨‍💻😎 #translationalmedicine #cancerresearch #martawylot #katrinaxian @cancercoreEU

Excited to share my latest PhD paper on centrosome amplification (CA) in ovarian cancer just published in Nature Communications! 📚Title: "Molecular landscape and functional characterization of centrosome amplification in ovarian cancer" 📎 Link to the Paper: doi.org/10.1038/s41467…

Our R package for visualizing chromosomes, genes, SVs and copy number is published now. Usage is simple and flexible! academic.oup.com/bioinformatics… github.com/cortes-ciriano…

To close 2023, we present our work on #osteosarcoma genome and clonal evolution biorxiv.org/content/10.110… How does #osteosarcoma arise? What rearrangement mechanisms cause some of the most complex #chromothripsis events seen in human cancer? Does chromothripsis occur subclonally?👇

We are recruiting this round! Apply to join our team! 😀

So excited to get this out - see great explainer thread below from Isidro Cortes-Ciriano on my main PhD project. Thanks so much to incredible collaborators and my amazing teammates! (Carolin Sauer, Jose Espejo Valle-Inclan, fmuyas, and everyone else in the Cortes-Ciriano lab)

Join us in welcoming Carolin Sauer, Postdoctoral Researcher, EMBL-EBI, to The Festival of Genomics & Biodata in London! She’ll explore the use of nanopore sequencing in liquid biopsy analysis for pediatric cancer patients. Register to join us: hubs.la/Q02TDtdC0 #FOG2025

Introducing SAVANA, a tool to detect somatic structural variants and copy number aberrations from long-read sequencing data with high sensitivity and specificity. nature.com/articles/s4159…