Interesting insight into research conducted by Thomas Böttcher and team on chemical interactions in the microbial world! Thank you, Thomas Böttcher, for being our guest at the Joint Microbiological Colloquium, today Controlling Microbes to Fight Infections Universität Tübingen! #ChemicalBiology #MicrobialBiochemistry

Together scientists of the DFG-funded transregional collaborative center #TRR261 from the Universities and University Hospitals at Tübingen and Bonn support the campaign and call for a prudent use of antibiotics and to prevent antibiotic resistance together. #WAAW2022

Of the 45 antibiotic candidates in global clinical development, just 27 target World Health Organization (WHO) priority pathogens. pew.org/3EF6NtK

Congratulations Lisa. Very much deserved.

Every year a new graphic ... I like them all. Thanks to Tanja Schneider. These are her ideas. She's so ceative.

Happy International Women's Day! We're celebrating women who have changed the world. Here's all of the amazing women who have received the #NobelPrize and their remarkable achievements at the time of the award. Who are the women who inspire you the most? #IWD2023

Dear community, the TRR261 conference is open to interested members of the international antibiotics and natural product community. We are happy that so many excellent speakers have followed our invitation. Registration portal will open soon. Check out under //trr261/news.

Happy women's day, today.

All the best for your start, Simon.

Organized by the TRR261, this conference is open to the entire natural products and antibiotics community!!! Antibiotic Action and Antibiotic Biosynthesis together in the same conference. This is rare but generates a lot of synergy. Register today as seats are filling rapidly !!

New paper with Peter Sass and Scott Ouellette. Chlamydial AAA+ unfoldase ClpC, its functional reconstitution, characterization, individually and in the ClpCP2P1 protease. Essential role for ClpC in chlamydial growth and intracellular development. journals.asm.org/doi/10.1128/mb…

Two PhD positons available in our team!!! Antibiotic MoA studies, including work on the fascinating target ClpP protase. One position within the Cluster of excellence CMFI cmfi.uni-tuebingen.de/and the second within the European Training Network CLEAR 'Cell Envelope Antibiotics'.

I am getting excited ... less than six weeks ahead ...

Dear Colleagues and friends ... thanks so much for making this event unforgetable.

"... the “pandemic treaty” must ... respond to a wider range of pandemic threats, not solely viruses ... If governments are serious about pandemic preparedness, they must support bold measures to conserve the effectiveness of antimicrobials within the Pandemic Instrument."

Job opening in my team!! Position for a PhD candidate in a soon to start Marie-Curie European Traning Network on cell envelope active antbiotics. Mode of action studies on new antibacterial agents. Please look at the attachement and spread the word. Thank you.

Happy to share our brandnew paper on the first natural product beta-lactone ClpP inhibitors. They bind covalently, inhibit virulence and gave beautiful co-crystal structures with ClpPs from all three domains of life. Thanks Groll, Kaysser, Sieber, Grond labs for excellent work !!

We are happy to share our new paper on the uptake of fosfomycin through porins of E. coli. Our data show that the cytoplasmic membrane is the rate-limiting barrier, unless the relevant transporters are induced. Thanks to ANTIBIOTIC CellMAP and Controlling Microbes to Fight Infections and the team. pubs.acs.org/doi/full/10.10…

Happy to report on epifadin, a new bacteriocin shaping the human microbiome. New structural class, very short lived. Kills S. aureus rapidly and gives the producer S. epidermidis a profound advantage. Thanks to the teams of Peschel, Krismer, Grond. rdcu.be/dtSW7

Great consortium! Looking very much forward to our joint research.