🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

For those interested, happy to announce I’ve set up a ko-fi page to simplify commissions of scientific portraits and illustrations of prerecorded talks. ko-fi.com/atjcagan/commi…

A postdoc with a newborn just told me daycare in Boston is ~$30,000/year 🤯 Despite having dual incomes, the cost is so prohibitive they are considering just going into industry... I wish there was a mechanism similar to the NIH Diversity Supplement to help parents with new borns

A great postdoc opportunity!

As it's #WomenInScience day: Some (if not the) best science in my lab has been done by extremely talented female scientists. Three examples of recent computational studies. And a great thank you! 👩‍💻👩‍💻👩‍💻

On this #WomenInScience day, I would like to highlight an institutional structure that makes it easier to be a woman in science. Yesterday, I was awarded a $50k Life Event Supplement to my NIH R15 grant! 🎉 1/

Come and join us! Whether you are computational yourself or just a secret admirer!

Let's be honest. You're nobody until you've been live-illustrated by Alex Cagan

Two international PhD positions available at our molecular biology institute in Brussels 🍟🍫🍺, for a varied range of topics. A couple bioinfo projects, too! Application by May 22nd. iribhmphd.ulb.be

Delighted to share our latest work in its final form (and open access!). Here, we studied the rate at which somatic mutations accumulate in different species to address some long-standing hypotheses. 🧵… 1/ nature.com/articles/s4158…

Incredibly excited to share our paper ‘Somatic mutation rates scale with lifespan across mammals’ now published @nature. nature.com/articles/s4158… An illustrated & updated tweetorial… [1/24]

If anyone had a doubt that somatic mosaicism is the next frontier in human genetics, here’s a case study: Exomes of 30K patients delivers the same gene that Campbell group discovered with somatic profiling of 30. 30K vs 30 🤯 nature.com/articles/s4158…

Lymphocytes have been genetically sequenced in higher resolution than ever before, uncovering more information about how mutations in these cells may influence the #ageing process and the development of certain #cancers 🔎🧬 bit.ly/3PgBdV3

As an undergrad, I told my advisor I had lots of ideas! Noah Rosenberg said, write them down. Maybe in a spreadsheet. I’m still using the same spreadsheet, just with many more tabs

Have to miss #Dros23 for family reasons. Sad esp bc I will miss the workshop that I & Bernard Kim organized on pop. genomics of all ~4K species of Drosophilidae. The vision is ~10 years old and I looked forward to the 1st public discussion. You shouldn't miss it! Fr7:45-9:45PM

Useful cheat-sheet of human pop gen numbers!

Re: the history of the DNA structure, see this blistering 1967 letter from Crick to Watson objecting to the draft of Watson’s book on their work. “...it shows such a naive and egotistical view of the subject as to be scarcely credible.” profiles.nlm.nih.gov/spotlight/sc/c…

I’m thrilled to shared that this August I’ll join the Department of Pathology of the University of Cambridge Cambridge University as a Group Leader. The Machado Lab will study the somatic evolution of the adaptive immune system to understand aging and disease.

Elegant study leveraging longitudinal blood sampling pre-AML diagnosis (up to 15 years prior!) to quantitatively describe blood cancer evolution.

Join us! The Machado Lab at Cambridge University is looking for an enthusiastic RA to be a core member of the team and lead the lab's data generation efforts, seeking to understand how tumour and immune cells co-evolve and contribute to cancer progression. jobs.cam.ac.uk/job/47922/

PhD and Postdoc positions available! Interested in how our immune system evolves with a growing tumour, and how we can use that to fight cancer? Love data analysis? Applications now being accepted in the Machado Lab (machado-lab.org/contact) at the University of Cambridge.