Hope Isobel Needs
@hopeneeds
ID: 1020428355206868993
20-07-2018 22:00:53
163 Tweet
247 Followers
573 Following
Fantastic responses to some pretty shocking "interviewing" 👏 #DontLookUp #RichardMadeley Gary Lineker #JustStopOil
Yay!! Thanks for a great viva @whitworth_lab and Mark Dodding! And thanks for amazing PhD supervision over the past 4.5 years Ian Collinson and Jeremy! Can't believe it's all over! 🥳🥳🥳
Anyone interested in doing a PhD in the Collinson Lab read on. Contact me by email or dm me for further details
The inimitable @LucyTroman ( Birkbeck, University of London ) & Alvira Collinson Lab latest work Bristol Biochemistry -intrigue in the bacterial envelope (and more to follow)! Collab with @the_gold_lab Bertram Daum of LSI Exeter; grateful to our funders SWBio DTP Biotechnology and Biological Sciences Research biorxiv.org/content/10.110…
First of my PhD work live on BioRXiV! Just in time for a quick holiday before we get back to work on the next installment! Thanks to co-authors Ian Collinson Gonçalo C. Pereira and Jeremy Henley! 🥳
Mess with the mitochondrial import machinery in neurones (including by disease-linked Tau) then this happens..... Another Hope Isobel Needs (Bristol Biochemistry Collinson Lab ) paper with the Henley lab. As ever thanks to our amazing funders Wellcome biorxiv.org/content/10.110…
What happens when the mitochondrial import machinery is troubled? Panic stations! One of Hope Isobel Needs (Bristol Biochemistry Collinson Lab) 3! new papers, also featuring Gonçalo C. Pereira, Emily Glover, Wolfgang Hübner & Jeremy Henley. Funded by Wellcome biorxiv.org/content/10.110…
Check out our new pre-print on the bacterial secretion machinery Amazing collaboration Collinson Lab RadfordLab Roman Tuma & Fessl Lab Achieved through the talents and years of hard work by Joel Crossley Will Allen & Dan Watkins Funded by @bbsrc 😊 doi.org/10.1101/793943
Paper 2/3 from my PhD work is now out J Cell Science dissecting the links between aggregation prone Tau and mitochondrial protein import! Thanks to co-authors Kevin Wilkinson, Jeremy Henley, and Ian Collinson, and J Cell Science for a smooth publication process! 🥳
We're really happy with the final version of Hope Isobel Needs J Cell Science paper from the Collinson Lab and Henley lab Bristol Biochemistry Funded by Wellcome journals.biologists.com/jcs/article/13…
In their #OpenAccess Research Article, Hope Isobel Needs, Kevin Wilkinson, Jeremy Henley & Ian Collinson Collinson Lab Bristol Biochemistry find that aggregation-prone Tau impairs mitochondrial import, affecting mitochondrial morphology & inducing neurodegeneration. journals.biologists.com/jcs/article/13…
Happy #FluorescenceFriday! This week we’re highlighting the effect of overproduction of aggregation-prone Tau on mitochondria from Hope Isobel Needs Kevin Wilkinson, Jeremy Henley & Ian Collinson Collinson Lab Bristol Biochemistry. journals.biologists.com/jcs/article/13… #microscopy #cellbiology #OpenAccess
Issue 13 is complete! Explore our ToC here: journals.biologists.com/jcs/issue/136/… Our cover image is a primary hippocampal neuron overproducing aggregation-prone Myc–TauP301L (green) & stained for ankyrin-G (magenta), a marker of the AIS. See Hope Isobel Needs et al. journals.biologists.com/jcs/article/13…
The last of my PhD work is finally out in Nature Communications 🥳 after a huge team effort over several years! Thanks and congrats to all fantastic co-authors Emily Glover Gonçalo C. Pereira Mark Dodding Ian Collinson (who led the show!), Alina Witt, Wolfgang Hübner, and Jeremy Henley!
Check out our latest methodological development with Natalie Niemi Hopefully, the start of a fruitful collaboration! Another Hope Isobel Needs paper! 👏👏👏 The MitoLuc assay for the analysis of the mechanism of mitochondrial p... sciencedirect.com/science/articl…