
Hui Chen
@hui_chen2
Postdoc in the Good Lab
ID: 1143179799159947264
24-06-2019 15:31:18
42 Tweet
87 Followers
167 Following



Transitions: Penn Medicine, UPenn CDB Matt Good and Hui Chen describe in Developmental Cell that the awakening of an embryo’s genome does not happen all at once, instead follows a pattern controlled by the various sizes of its cells. NIH, BWFUND, March of Dimes. bit.ly/2IorqNq



There is a transition during early development when an embryo undergoes biochemical changes, switching from being controlled by maternal molecules to being governed by its own genome, according to new Penn Medicine research. bit.ly/2XAQQA3


First time attending the @___SDB___ meeting #2019SDB and it was my great honor to present in the BEST Hilde Mangold Postdoctoral Symposium. Many thanks to you Lila Solnica Krezel 🇺🇦 A. Sánchez Alvarado Jeff Farrell Tania, Natalia and DevelopmentalDynamic.

Our method on imaging single-cell nascent transcription in wholemount early embryos to reveal a novel spatial pattern of ZGA. Special thanks to John Wallingford and @mechmorph for their pioneering imaging techniques, National Xenopus Resource for training and @CDBMicroCore for technical support.

Our preview Developmental Cell for the beautiful work on nuclear size control by perinuclear ER from the labs of Nicolas Minc and Dan Levy. Congrats to Nicolas and Dan!

Excited to share new work from our lab that uncovers mechanisms regulating genome activation in early development. Heroic effort from Hui Chen to spatially map nascent transcriptome, and uncover precocious ZGA. Out online Current Biology. Free access: authors.elsevier.com/a/1fe3c3QW8R%7…