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Limiting sugar in the first 1000 days of life reduces diabetes and hypertension risk by about 35% and 20% science.org/doi/10.1126/sc…

New Cancer Immunology Research paper from Humam Kadara Zahraa Rahal & colleagues MD Anderson Cancer Center Inflammation Mediated by Gut #Microbiome Alterations Promotes #LungCancer Development and an Immunosuppressed Tumor Microenvironment aacrjournals.org/cancerimmunolr…

Please check our group’s poster 1263 at #SITC24 on effects of high fiber diet on the gut #microbiome, tumor immunity and lung cancer development. Congrats to postdoc fellow in our group Manvi Sharma for presenting this work today and receiving a SITC young investigator award!

Please check out Zahraa Rahal poster 565 with Tina Cascone at #SITC24 on spatial omics analysis of #lungcancer following neoadjuvant chemoimmunotherapy! MD Anderson Cancer Center #endcancer

Our postdoctoral fellow Dr. @Manvi_Sharma1 of MD Anderson’s Dr. @Humam_Kadara lab shared findings on the impact of dietary fiber on the gut microbiome, with implications for effects on immunotherapy response (Abstract 1263). @SITCancer #SITC24 #EndCancer

New NEJM A whopping (~90%) reduction of progression to Type 2 diabetes with tirzepatide (GLP-1 drug, dual receptor) vs placebo in a randomized trial of >2,500 participants with obesity, absolute reduction of 10/100 treated nejm.org/doi/full/10.10… by Ania M. Jastreboff, MD, PhD and

Congrats to MD Anderson-UTH Grad student in the lab Yuejiang Liu for receiving the American Legion Auxiliary Fellowship for her work on role of inflammation propagated by gut #microbiome alterations on #lungcancer development. Very proud of you, Cindy!

Excited to share our latest work! 📖 🔍 Mapping the earliest events of lung carcinogenesis to pave the way for cancer interception. 💡🫁 Sarah Mazzilli Humam Kadara Nature Reviews Cancer #CancerResearch #LungCancer #NSCLC

#NIH study section I serve on got cancelled, reviews from everyone were in on time. Do not regret one bit completing all reviews. It is our collective responsibility to keep moving the science forward even in difficult times.

After 16 papers and wonderful moments in science, our superstar postdoc fellow is on to her next step in what is a surely glorious career. Here we are discussing science even on a nice Saturday morning. Onwards and upwards Zahraa Rahal. I’m so proud of you 🙏.

HUGE congratulations to Linghua Wang, MD, PhD & team for her latest Cancer Cell study Integrative analyses of over 14 million cells from 10 cancer types across 7 spatial transcriptomics and proteomics platforms identifies four distinct spatial CAF subtypes conserved across cancer types

🙏 I am very grateful to be awarded the Elza A. and Ina Shackelford Freeman Endowed Professorship at MD Anderson Cancer Center . Many thanks to trainees, colleagues, mentors, friends and family who continue to inspire me in my journey.

Please check out Zahraa Rahal minisymposium presentation (abstract 6384) at #AACR25 in which she finds a target that mediates development of KRAS-mutant #lungcancer and response to KRAS-targeted therapy

In a presentation at #AACR25, Dr. Zahraa Rahal shared research that found protein CD24 promotes development of KRAS-mutant lung adenocarcinoma and contributes to KRAS inhibitor resistance. Read more: bit.ly/4iNWGDL Zahraa Rahal #EndCancer

Honored to present our work around the identification of #CREM as a regulatory checkpoint of CAR and cytokine signaling at #AACR25. Grateful to Katy Rezvani, M.D., Ph.D for her support over the years and to MD Anderson Cancer Center for being the best place for #cancerresearch. Excited to advance this

Congratulations dear Yuejiang Liu for receiving an F31 predoctoral fellowship from the NCI. Very proud of you Cindy!

Conserved spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts revealed by single-cell spatial multi-omics dlvr.it/TKm6gd

(1/9) Thrilled and honored to share our NatureRevClinOncol comprehensive review dissecting the crosstalk between non-small-cell lung cancer (NSCLC) and its tumour microenvironment (TME), and how it drives progression & response to therapy. ➡️ nature.com/articles/s4157…

🧵1/ T cells have deservedly been in the🔦for #cancer #immunotherapy, but other engineered cell therapies are now📈. What mediates NK cell exhaustion remains an important unanswered❓. 📄Link: nature.com/articles/s4158… I’m so thrilled🥳to share our work out now🚨nature

🧬 New NatureRevClinOncol review breaks down the NSCLC tumor microenvironment: ▪️CAFs, cytokines, checkpoints ▪️From cold to hot & back again ▪️Resistance, remodeling and response nature.com/articles/s4157… 🌪️ Immunity isn’t a solo — it’s a crosstalk concerto 🎻 Listen closely.