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Spectacular talk by Ben Winer postdoc from our friendly neighbor The Morgan Huse Laboratory at the 2023 Phagocyte GRC! Please stay on the look out for his work 👀

And as an encore from The Morgan Huse Laboratory we get to see even more of their awesome science at the #Phagocyte #GRC poster session! Ben Winer again featured along with graduate student Alex Settle.

It’s been quite a month for the Huse lab’s own Dr. Elisa Sanchez! A brand new baby girl (Amelia) and a brand new paper in Nature Immunology about how cytotoxic T cells release dying target cells. Read more about it here: nature.com/articles/s4159… and here: nature.com/articles/s4159…

Hi everyone, I’m excited to share a pre-print of my postdoc work 🍾biorxiv.org/content/10.110… We found a protein (Gb4) that allows immune cells to move after ”eating”. Normal innate immune cells (red) stop moving to prevent pathogen spreading, but cells lacking Gb4 keep migrating.

New research from postdoctoral fellow Ben Winer!  Plasma membrane abundance functions as a biophysical master regulator of both phagocytosis and migration in myeloid cells. Read more about it on biorxiv (biorxiv.org/content/10.110…)

Congratulations to Ben for winning the award for best postdoc talk at the IMP retreat!

When you accidentally drop your GL14 funnel into the glassware tub The Morgan Huse Laboratory, just fish it out with our serological chopsticks. #phdlife #thescientist #nobodysaiditwaseasy

My 7-yr #PhD The Morgan Huse Laboratory GSK Graduate School summarized in 10 s: the #Tcell #immunesynapse squishes & micropatterns target cells! A close look at the surface patterns shows how "Rippling" and "Killing" are associated - so yes, T cells mastered Hamon right out of #JoJosBizzareAdventure.

Yassmin stars in the new Gerstner Sloan Kettering Graduate School recruitment video! Link below. mskcc.org/videos/trainin…

Exciting new research from our lab, led by PhD student Alex Settle, is up now on BioRxiv! Using deformable hydrogel particles, we explored how macrophages respond to the rigidity of their targets during phagocytosis! Check it out now. biorxiv.org/content/10.110…

Our paper on plasma membrane abundance and phagocytosis is out in Science Immunology! Congratulations to ace myeloid mechanobiologist Ben Winer (Ben Winer) and also to our collaborators Orion Weiner (Weiner Lab) and Jason Cyster. science.org/doi/10.1126/sc…

Researchers show that cytotoxic #Tcells actively compress and pattern their targets within the #immune synapse to maximize their cell-killing potential. The Morgan Huse Laboratory Learn more in Science #Immunology: scim.ag/7v9

Our paper describing the death grip cytotoxic T cells use to kill their prey is out in Science Immunology! Congratulations to Miguel DJ and Alex Settle, our resident leukocyte topographers. science.org/doi/10.1126/sc…

What happens when a #cytotoxic #Tcell, a cartographer, and David Attenborough walk into a bar? I'm not too sure, but our story in Science Immunology might tickle your fancy. #immunology #synapse #biomechanics

Our paper is out today in Science Immunology! A really fun project to work on with Miguel DJ. Check out my thread from last April for an explainer: science.org/doi/10.1126/sc…

Really appreciate this highlight in nature of my #PhD story Science Immunology! The immune system is full of drama! The Morgan Huse Laboratory nature.com/articles/d4158…

Congratulations to the Huse lab’s newest Ph.D., Alex Settle! Alex’s paper on integrin mechanosensing during macrophage phagocytosis was just published in Nature Communications! nature.com/articles/s4146…

Our new review on the mechanoregulation of cytotoxic lymphocytes is out in Nature Reviews Immunology! nature.com/articles/s4157…

Congratulations to our latest graduate, Dr. Diana Tran!

Check out our new preprint! Graduate student Yassmin Elbanna and friends have found that the mechanical rigidity of the metastatic microenvironment controls the efficiency of anti-tumor immunosurveillance. biorxiv.org/content/10.110…