🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Nice Review from the collaboration between Jianjun Cheng lab and our lab: Serotonin 2A Receptor (5-HT2AR) Agonists: Psychedelics and Non-Hallucinogenic Analogues as Emerging Antidepressants | Chemical Reviews pubs.acs.org/doi/10.1021/ac…

📢Preprint Alarm🚨 biorxiv.org/content/10.110… In a first collaboration with the Stoeber lab Miriam Stoeber we characterise an extracellular nanobody (NbE) that binds as an antagonists to the µ-opioid receptor. This work was driven by Jun Yu jun and Amit Kumar🌟🌟

Wow, many congrats to Hye Jin Kang and BryanRoth! Great and Informative Review on Chemogenetics!

This weeks PrimeView highlights the utility of designer receptors exclusively activated by designer drugs (DREADDs) in neuroscience to study neuronal activity and signalling in cells, rodents and non-human primates. Free to donwload for a week! go.nature.com/3GKClP4

📢 Don't miss what everyone is reading! 👀 This recent article has over 2,400 views: 📑 Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator 🖊 Brian Krumm et al from Bryan Roth BryanRoth Read here ➡ go.acs.org/7oo

"Pharmacology is the chemical control of physiology" (Terry Kenakin at Bryan Roth meeting today)

YUUGE paper just dropped with amazing results!! AlphaFold2 structures template ligand discovery | bioRxiv biorxiv.org/content/10.110…

Coming soon 😎🙏.

A fully funded postdoctoral position available to study cell biology of GPCRs. Experience in microscopy highly desirable. Please RT. pdsp.unc.edu/rothlab/public…

Congrats to Yoojoong Kim Ryan Gumpper Bryan Roth Bitter taste receptor activation by cholesterol and an intracellular tastant nature.com/articles/s4158…

My first paper from the Roth lab is finally out! Huge thanks to everyone involved, especially Bryan BryanRoth . This wouldn't have been possible without Bryan's support and the incredible team Bryan Roth nature.com/articles/s4158…

Intracellular tastant !!! Many Congrats to Yoojoong Kim Ryan Gumpper Yongfeng Liu BryanRoth, and Roth lab Bryan Roth !!!🥳

Serotonin receptors control mood, emotion, and many other behaviors, and are targets for many important drugs More on #PeakPerformance at PDB-101 pdb101.rcsb.org/motm/164

Lessons from a Toad Psychedelic about the Role of different Serotonin Receptors in Psychedelic Physiology: nature.com/articles/s4158… Congrats to Audrey and David Lankri in this collab with SamesLab and Scott Russo published in nature

Protein prediction technology yields accurate results to efficiently find the best drug candidate for many conditions phys.org/news/2024-05-p… via Phys.org

📢#GPCR ECIs, mark your calendar for the next Transatlantic GPCR Symposium! The event will happen on September 5-6th, 2024 and the registration is already open. The event will host two excellent keynote speakers, Dr. Maria Marti-Solao and Dr. Aashish Manglik. So, don't miss it!

Today in nature we present the results of our exploration of the soluble protein universe and the design of functional soluble membrane proteins with Casper Goverde Nico Goldbach Bruno Correia 1/6 nature.com/articles/s4158…

Happy to share that this work on the structural biology of #psychedelics is finally out! Big shout out to all involved, especially BryanRoth for all of the support! The structural diversity of psychedelic drug actions revealed | Nature Communications nature.com/articles/s4146…

In our new Ask the Author feature, we speak to Professor Bryan Roth about his team’s new HCAD chemogenetic system. 👨‍🔬 BryanRoth tells us what makes HCAD different, and why Hello Bio's FCH-2296413 proved such a valuable research tool: ow.ly/NpBq50W7LXH #chemogenetics