Ever heard of the Trojan Horse? In our most recent preprint we show how neomorphic DNA binding of fusion transcription factors can be exploited for therapeutic gene expression in oncogene-addicted pediatric sarcoma! So happy to see this out! biorxiv.org/content/10.110…

Very happy to share these news! Thanks to Veit Hornung HornungLab for the great support and the productive scientific environment established for this achievement! 🥳

Excited to share our latest study in Immunity showing how PLD exonucleases together with RNase T2 process RNA upstream of TLR7. ✂️🧬 Kudos to Marleen Bérouti for her fantastic work! cell.com/immunity/fullt…

Read our paper in JHEP Reports on the risk of bleeding and thromboembolism in atezobev vs lenvatinib for HCC. Big thanks to the fantastic collaborators!

🚨 Reminder! 🚨 Be sure to submit your abstract for our upcoming EMBO workshop "The Inflammasomes 2024"! 📅 - Many opportunities for short talks 🎤 - Several travel grants available 🌍 - Lots of networking opportunities 🤝 - 🥨& 🍻 meetings.embo.org/event/24-infla…

Final call to register for our EMBO Workshop! The Inflammasomes - 2024 24 – 27 September 2024 | Planegg-Martinsried, Germany

We’ve just finalized the program for our EMBO Inflammasome Workshop. 🙌 Next to many amazing short talks, we have an incredible lineup of poster presentations featuring lots of unpublished work. Check out the full agenda on our website—there’s still time to register! 👇

📢Don't miss this great job opportunity: HornungLab invites applications for a ‼️postdoctoral position‼️ to investigate the fundamental question of how the innate immune system distinguishes self from non-self 🧐genzentrum.uni-muenchen.de/career/postdoc… Veit Hornung

📢 Postdoc opening! 📢 Sorek Lab and HornungLab are looking for outstanding candidates for a position at the intersection of computational biology & innate immunity. Dive into impactful research across two dynamic fields. Interested? Let’s connect! 👇 genzentrum.uni-muenchen.de/career/postdoc…

🔬 Nukleinsäuren können mehr als Gene speichern – und #NUCLEATE will das volle Potenzial nutzen. Mit dem neuen #Exzellenzcluster erforschen #LMU, TU München & Universität Würzburg #UniWürzburg DNA & RNA interdisziplinär – von Gentherapie bis KI. #Forschung #Biotech lmu.de/de/newsroom/ne…

Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement Cell Thomas Carell Veit Hornung Marleen Bérouti cell.com/cell/fulltext/…

🥳Amazing publication from the HornungLab, in collab. with the Thomas Carell lab, on the innate immune system: how modified RNA tricks the immune system. Big shout-out to the two first authors, Marleen Bérouti and Mirko Wagner! sciencedirect.com/science/articl… lmu.de/en/newsroom/ne…

🏥Early mortality in atezo-beva for HCC JHEP Reports 🚨CPS B and high CRP ➡️ early mortality (90days) ❗️Among patients with CPS B: B9, ECOG ≥2, high creatinin 👉jhep-reports.eu/article/S2589-… #cancer #oncology #MedX #liver OncoAlert

Great to see our new study on a vulnerable phase in HCC immunotherapy highlighted. Thank you Erman Akkus, and thanks to all collaborators!

Great collaborative effort 🥂Ignazio Piseddu #Anzlab Enrico De Toni Katrin Böttcher Julia MAYERLE

Deep Immune Phenotyping Reveals Distinct Immunopathogenesis in Checkpoint Inhibitor–Induced Colitis Compared with Ulcerative Colitis: brnw.ch/21wUjA3