Iain Cheeseman (@iaincheeseman) 's Twitter Profile
Iain Cheeseman

@iaincheeseman

Whitehead Institute and Department of Biology, MIT. Lover of cell biology and cell division. Aspiring to do good science and to do good.

ID: 598371517

linkhttp://cheesemanlab.wi.mit.edu calendar_today03-06-2012 14:18:57

2,2K Tweet

7,7K Followers

858 Following

Whitehead Institute (@whiteheadinst) 's Twitter Profile Photo

"Cells have axes of control that they use to quickly make broad changes in gene expression...Our work identifies another axis of control, and we’re excited to discover more about when and how cells make use of it," Iain Cheeseman says. wi.mit.edu/news/elegant-s…

"Cells have axes of control that they use to quickly make broad changes in gene expression...Our work identifies another axis of control, and we’re excited to discover more about when and how cells make use of it," <a href="/iaincheeseman/">Iain Cheeseman</a> says. wi.mit.edu/news/elegant-s…
Science in Boston (@scienceinboston) 's Twitter Profile Photo

🧫 Dr. Iain Cheeseman and his lab at the Whitehead Institute and Massachusetts Institute of Technology (MIT) have identified how cells switch to a different pattern of protein variant production using #eIF1 during #mitosis. 📰 Press release: bit.ly/3NVbZgQ 🔗 Abstract in nature: go.nature.com/3NRqxOu

🧫 Dr. <a href="/iaincheeseman/">Iain Cheeseman</a> and his lab at the <a href="/WhiteheadInst/">Whitehead Institute</a> and <a href="/MIT/">Massachusetts Institute of Technology (MIT)</a> have identified how cells switch to a different pattern of protein variant production using #eIF1 during #mitosis. 

📰 Press release: bit.ly/3NVbZgQ
🔗 Abstract in <a href="/Nature/">nature</a>: go.nature.com/3NRqxOu
Whitehead Institute (@whiteheadinst) 's Twitter Profile Photo

"For a long time, people didn’t think much protein production happened in mitosis at all. It was satisfying to show not only that it is occurring, but that there’s a shift in which proteins are being made," graduate student Jimmy Ly says. wi.mit.edu/news/elegant-s…

"For a long time, people didn’t think much protein production happened in mitosis at all. It was satisfying to show not only that it is occurring, but that there’s a shift in which proteins are being made," graduate student Jimmy Ly says. wi.mit.edu/news/elegant-s…
Journal of Cell Biology (@jcellbiol) 's Twitter Profile Photo

Su, Radul, Maier, Tsang, Iain Cheeseman et al Whitehead Institute use #CRISPR/Cas9 functional genetic screens to reveal factors affecting cell sensitivity to antimicrotubule drugs, revealing new players in #microtubule function & new roles for established MAPs hubs.la/Q02Z4b_B0

Su, Radul, Maier, Tsang, <a href="/iaincheeseman/">Iain Cheeseman</a> et al <a href="/WhiteheadInst/">Whitehead Institute</a> use #CRISPR/Cas9 functional genetic screens to reveal factors affecting cell sensitivity to antimicrotubule drugs, revealing new players in #microtubule function &amp; new roles for established MAPs hubs.la/Q02Z4b_B0
Journal of Cell Biology (@jcellbiol) 's Twitter Profile Photo

Functional genetics reveals modulators of antimicrotubule drug sensitivity. New study from Kuan-Chung Su, Elena Radul, Nolan Maier, Mary-Jane Tsang, Iain Cheeseman Iain Cheeseman and colleagues Whitehead Institute: hubs.la/Q02Z44f60 #Microtubules #CellDivision #Cytoskeleton

Functional genetics reveals modulators of antimicrotubule drug sensitivity. New study from Kuan-Chung Su, Elena Radul, Nolan Maier, Mary-Jane Tsang, Iain Cheeseman <a href="/iaincheeseman/">Iain Cheeseman</a> and colleagues <a href="/WhiteheadInst/">Whitehead Institute</a>: hubs.la/Q02Z44f60 

#Microtubules #CellDivision #Cytoskeleton
Ally_Nguyen (@allynguyen9) 's Twitter Profile Photo

Excited to share that the Nguyen lab website is live Nguyenlab.org ! Check out what we are working on and if you are at ASCB next week come say hello! We will be presenting a poster Monday at board B277

Iain Cheeseman (@iaincheeseman) 's Twitter Profile Photo

New preprint w/ surprising insights into proteasomes + mitosis. Océane Marescal found strikingly different cellular phenotypes for proteasome knockouts. 19S lid depletion results in ubiquitin-INDEPENDENT degradation of KIF11 motor + monopolar spindles. biorxiv.org/content/10.110…

Iain Cheeseman (@iaincheeseman) 's Twitter Profile Photo

New preprint! Eric Smith + Jimmy Ly reveal a beautiful example of repurposing of a molecular machine. RNase P + RNase MRP share 9 subunits and yet are functionally very different. We find key new subunits that act as specificity factors to distinguish MRP. biorxiv.org/content/10.110…

New preprint! Eric Smith + Jimmy Ly reveal a beautiful example of repurposing of a molecular machine. RNase P + RNase MRP share 9 subunits and yet are functionally very different. We find key new subunits that act as specificity factors to distinguish MRP.
biorxiv.org/content/10.110…
Whitehead Institute (@whiteheadinst) 's Twitter Profile Photo

Researchers in the Cheeseman lab have identified an important molecular switch that induces a distinct pattern of protein variant production during mitosis. #ResearchHighlights

Iain Cheeseman (@iaincheeseman) 's Twitter Profile Photo

New preprint drop! Check out work from Jimmy Ly et al for how protein isoforms generated by alternate translation initiation create dual localization, contribute to mitochondrial function, and are mutated in disease. Tweet-tutorial thread below. biorxiv.org/content/10.110…

Iain Cheeseman (@iaincheeseman) 's Twitter Profile Photo

Optical Pooled Screening has transformed large-scale cell biology, but lacks robust end-to-end computational strategies to process these Tb-sized datasets. New from Di Bernardo et al (Matteo Di Bernardo): Brieflow. A game changer for OPS + new biological insights biorxiv.org/content/10.110…

Matteo Di Bernardo (@mat10_d) 's Twitter Profile Photo

Optical pooled screening is revolutionizing functional genomics by linking genetic perturbations to complex cellular phenotypes at unprecedented scale. But analyzing these massive datasets has been a major bottleneck - researchers face fragmented tools, multiple format

Optical pooled screening is revolutionizing functional genomics by linking genetic perturbations to complex cellular phenotypes at unprecedented scale. But analyzing these massive datasets has been a major bottleneck - researchers face fragmented tools, multiple format