
Sophia Liu
@immunoliugy
Early Independence Fellow @ragoninstitute | immunology, engineering, spatial & temporal methods | Ph.D. @Harvard Biophysics @mit_hst B.S. @MITChemE
ID: 2711119902
https://www.liulab.bio 06-08-2014 04:45:56
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7 years ago, I met a junior fellow named Jason Buenrostro who blew me away with a vision of futuristic genomic technologies Today, we (Ajay Labade, @carolinecomenho) are excited to share our first steps into that future: Expansion in situ genome sequencing 1/

A wonderful collaborative effort in the lab by Dennis Gong Ella Perrault Jung Woo Bae #JeannaQiu just published in Cancer Cell👇tinyurl.com/bdhcbu5t We hope this is a useful resource for anyone interested in #SpatialOncology!



Just out: our latest review in Science Magazine, led by Immunosurveillance @TheCrick & @KingsCollegeLon :) science.org/doi/10.1126/sc…

Spread the word! MIT IMES is seeking a tenure track junior faculty candidate in #healthsciences. IMES is at the convergence of #Engineering , #Science , and #medicine to transform #humanhealth for all. Massachusetts Institute of Technology (MIT) MIT School of Engineering HST Learn more here: bit.ly/3TXpsYS


I am happy to share a large part of my postdoctoral work published in Science Immunology! Using LIPSTIC, we identify and characterize antigen-presenting dendritic cells (DCs) in the tumor-draining lymph node and tumor microenvironment science.org/doi/10.1126/sc…

Paper alert: Congratulations to PhD student, now Dr. Aryeh Solomon for this great work, published eLife - the journal. Can a BCG vaccine also protect from Gram-negative infection? #TrainedImmunity Thanks also to long time collaborator Mihai Netea and other friends. doi.org/10.7554/eLife.…


Really excited to share work from our team at Ginkgo Bioworks, led by Alyssa Morrow, on ML guided 3’ UTR design. biorxiv.org/content/10.110… It's a great story of dataset generation, model training, generative design, in-vivo validation, and model release. More details in thread!

Our paper on continuous mutagenesis in living cells using HACE is now out in Science Magazine! We now demonstrate that HACE continuously generates mutations over a 10-day period and enables targeting using dCas9 without introducing DNA nicks. science.org/doi/10.1126/sc…


a personal update: in January, I'm moving to Yale to join Department of MCDB and to open my lab in the Wu Tsai Institute | Yale University Institute! We will investigate multicellular self-organization using synbio tools to read and write developmental signals in stem cell models. syndevbio.org


excited to share & release ProtNote! 🧬📰 ProtNote enables protein-function annotation on new, unseen functions by fusing LLM embeddings of text descriptions w/ protein sequence embeddings 📎biorxiv.org/content/10.110… 🖥️ github.com/microsoft/prot… led by the incredible Samir Char




