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Tomorrow is the beginning of the European Organ-on-Chip Society Conference and we are excited to be part of it this year! Join us at the event and have a look at our FLEXcyte poster (number 23). #EUROoCS21 #organonchip #Cardiomyocytes #Conferences #toxicology #safety #preclinical

Do you want to learn about the FLEXcyte technology, how it works and what it's used for in less than 5 minutes? Watch the ACTC conference flash talk here: lnkd.in/dN-FhS2 #conference #cardiacsafety #toxicity #preclinical #drugdevelopment #animalfree

July's #innovation series article demonstrates the importance of RYR2 #calcium channel for the contractile function of human iPSC-cardiomyocytes and identifies an IP3R-mediated compensatory calcium mechanism in RYR2-/- lines. innovitro.de/news/innovatio… #iPS #Cardiomyocytes #calcium

The 11th World Congress on Alternatives and Animal Use in the Life Sciences is up & running with innoVitro on board! Matthias Gossmann will present our poster (P573) live during the sessions this friday and next tuesday! Come and visit! #WC11Maastricht #animalfree #DD #IPS

With our partners FZJ and beniag, we optically paced iCell CM2 cultured on FLEXcyte 96 plates in less than a week.Cells were transfected with Channelrhodopsin2 and analyzed 24h later by light induced stimulation performed with the FLEXcyte system. innovitro.de/flexcyte-techn… #iPS #DD

Finally - the Safety Pharmacology Society annual meeting started today! Visit our booth and talk to us about your preclinical cardiac safety testing-are you working animal-free already? #SPSVirtual2021 #preclinical #cardiacsafety #cardiomyocytes #contractility #drugdevelopment

Check out our SPS 2021 poster showing how the physiological FLEXcyte environment alters gene expression, phenotype and functional properties of human iPSC-derived #cardiomyocytes towards more mature state lnkd.in/dAt_wS2 #preclinical #iPS #SPSvirtual2021 #DrugDevelopment

... remember Laura? Watch the new video to find out how Laura - the cardiac safety researcher - uses the FLEXcyte 96 to analyse contractile force of human iPSC-derived cardiomyocytes! lnkd.in/dAykKuKa #preclinical #drugdevelopment #contractility #ips #Pharmacology #FORCE

Follow our new innovation facts blog focussing on news on FLEXcyte technology and related topics! In this first part, we show you how to use the physiological environment of the FLEXcyte plate over time to push maturation in vitro. lnkd.in/dZprnT5Q #CRO #drugdevelopment

The December issue of the innovation series comes from Cui et al., 2019 and underlines once again how important mature #hiPSC - #cardiomyocytes are for investigating tox effects reliably for human cancer treatment! lnkd.in/dvVKxp9N #CRO #drugdevelopment #cardiacsafety #IPS

Part 2. of the innoVation Facts series addresses #cardiac maturation cues. We focus on phenotypic changes that take place when human #iPSCs #cardiomyocytes are cultured on FLEXcyte 96 plates to emulate the physiological conditions of the human heart. lnkd.in/e2htv_Cg #CRO

The innoVitro team wishes you a very happy holiday season and a prosperous and peaceful New Year! See you in 2022!

We start the new year with an article by Lebrec et al., 2021 covering CAR-T / TCR immunotherapy research findings with a focus on #nonclinical safety evaluation. lnkd.in/e_U3VfZi #immunotherapy #CART #drugdevelopment #safety #innovation

Part 3 of the #innoVation Facts series about #cardiac maturation cues shows upregulated expression of genes important for contractility & morphology in hiPSC-CMs cultured on FLEXcyte plates. Improve human #preclinical cardiac risk to more adult state! lnkd.in/eJ9hHdKZ #IPS

Will you attend the Biophysical Society Meeting in San Francisco as well? Come and meet us at booth 629! We can't wait to have an in-person conversation after two years of virtual events! #conference #Biophysics #BPS22

A newly published article assessing hiPSC-CM #contractility kinetics caught our interest this month. The data shows that flexible substrates are necessary for normal twitch-like contractility kinetics & interpretation of #inotropic interventions. lnkd.in/eGBXzXfM #iPS #CRO

Only a few more days to go... Come and see us at the Biophysical Society Meeting in San Francisco next week. We are looking forward to having great chats with you in person! #drugdevelopment #bps2022 #drugdiscovery #preclinical

In the March issue of the #innovation Series a study of #cardiac cells and their gene expression profiles was performed. Six anatomical adult #heart regions were analyzed to establish a cardiac cell atlas for better understanding of the human heart. lnkd.in/e3x28N-J

innoVitro has been recognized by GHP as most innovative in vitro technology company in Germany for the year 2022. Read the full interview here lnkd.in/eNUaccSV #award #innovation #biotechnology #iPS #FLEXcyte #contractility #drugdevelopment

Watch this lovely animation video produced by the Projektträger Karlsruhe, that explains the FLEXcyte technology's impact in DD for our younger generations! lnkd.in/eAnVhqB2 #video #animation #FLEXcyte #iPS #drugdevelopment #DD