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UniProt is at #PAG32 Sun 12th 11.30-12.00 (PST) ‘UniProt Database’ – Genome annotation resources at the EBI – Town & County Mon 13th 10.00-11.30 Poster P100 Tue 14th Jan 17.20-17.35 – ‘Proteomics data in UniProt’– Proteomics – Pacific D lnkd.in/eYBNjPEy PAG 31 / PAG Australia / PAG Asia

Dive into a world of protein-protein interactions (PPIs) with an IntAct tour! 🚀 Take our quick tour and discover: • How to search for PPIs • Tools to visualize networks • Easy options to download data • How to submit your own data tinyurl.com/wupz8h4k #ProteinInteractions

🚧 Essential maintenance is planned to begin on Friday January 24th 2025. 🔧 The UniProt website may be temporarily unavailable. If this happens, please use our fallback wwwdev.ebi.ac.uk/uniprot/front-… during this time.

Join us with UniProt to discover two automated annotation systems UniRule and ARBA and their use in functional annotation of proteins. Registration is free but essential ebi.ac.uk/training/event… EMBL-EBI #proteomics #OpenAccess

Start 2025 with a look at the Prefoldin-like co-chaperone complex (tinyurl.com/3p8b2arh), it’s multi-functional with roles in proteostasis, protein folding, assembly and stabilization. Visit us to learn more about this and Prefoldin (CPX-6149) & PAQosome (CPX-6145) complexes!

👩‍🔬 Today is International Women and Girls in Science day! 🧪 To celebrate we’re shining the spotlight on two biocurators at the Complex Portal.

👩‍🔬 Today is International Women and Girls in Science day! 🧪 To celebrate we’re shining the spotlight on two biocurators at the Complex Portal.

👩‍🔬 Today is International Women and Girls in Science day! 🧪 To celebrate we’re shining the spotlight on two members of the IntAct Team.

👩‍🔬 Today is International Women and Girls in Science day! 🧪 To celebrate we’re shining the spotlight on two members of the IntAct team.

Interested in RASopathy and RAS-driven cancers? This month we feature SHOC-MRAS holophosphatase complexes.....CPX-25716, CPX-25719, CPX-25720. Visit the Complex Portal to learn more!

IntAct release 250 is out! 1,702,367 binary interactions from 23,612 manually curated publications ebi.ac.uk/intact/about#s… (in sync with UniProt release 2025_02)

IntAct is expanding its Inflammatory Bowel Disease dataset (lnkd.in/ejkr8tKx)! Our latest addition is the lncRNA GATA6-AS1 interactome, from K.E. Sosnovski et al. (2023) in Caco-2 cells (lnkd.in/eiYaFSdK). ➡️ Learn more about this! (lnkd.in/e2RSQEZZ)

Excited to have integrated data from ‘Systematic discovery of mutation-directed neo-protein-protein interactions in cancer’ in IntAct (PMID: 35512704). #tumor #PPI #mutations Explore the interactome at ebi.ac.uk/intact/search?…

Thrilled to announce that the protein–protein interactions of 396 SLC transporters, from the RESOLUTE project, is now integrated into IntAct! Congratulations to #Superti-FurgaLab, #FabianFrommelt Explore the interactome at ebi.ac.uk/intact/search?…

May is skin cancer awareness month! We're highlighting Telomerase holoenzyme complex (CPX-265) featuring TERT(UniProt:O14746). See the complex in tinyurl.com/mt7u4wbs & visit UniProt for all melanoma-associated proteins tinyurl.com/mryjvyu7 #MelanomaAwareness, #SunSafety🧴

It is Skin Cancer awareness month! Explore manually curated interactomes of proteins associated with familial melanoma in IntAct. Access the network in IntAct (tinyurl.com/26tc7xtm). #IntAct_EBI, #ComplexPortal, #UniProt, #MelanomaAwareness, #SunSafety, 😎📷🧴

Now published in Mol Syst Biol embopress.org/doi/full/10.10…

IntAct's dataset of the month features 75 cancer-associated missense variants in retinoblastoma tumor suppressor protein (PMID:39938803). Visit IntAct & explore detailed expert-curation of variants, binding domains and biophysical parameters (tinyurl.com/4rsx8754). #Cancer

UniProt is a world-leading, freely accessible data resource that provides protein sequence and functional information to scientists worldwide. So what is the value of UniProt for the global scientific community? #FAIRdata #Bioinformatics