Research from NMHI member Maria Ioannou has shown that fat in the brain could be key to new treatments for Parkinson’s disease. ualberta.ca/folio/2024/03/…

New paper from our lab out now in Current Biology. Our contribution to the argument that our favourite elusive brain region - the claustrum - is a critical pain processing node. cell.com/current-biolog…

Following up on Anna Taylor's tweet, for Christian's paper: cell.com/current-biolog… We're looking to add some keen graduate, postdocs, and RA's to the team. Projects focused on claustrum, pain, unconsciousness, etc. Reach out to Anna or I if you are interested.

Excited to share our review on axonal lysosome transport and its links to neurological diseases: sciencedirect.com/science/articl…

rdcu.be/dMdQ9   Excited and proud to see the final version of our manuscript out Nature Communications, describing a new lipid droplet reporter mouse, which allows staining-free fluorescent visualization of #LipidDroplets!! Check out how numerous they are in the brain!

Neuronal ferroptosis is central to neurological diseases: here we are discussing alterations in iron & lipid metabolism, neuronal vulnerability and protective strategies. Finally, the reciprocal roles of iron, lipids, and pathogenic proteins in ferroptosis. Cover design: me 🥰

Mark your calendars! The 1st FASEB #Ferroptosis conference, July 27-31 2025! We just posted our preliminary agenda! Spectacular line up and lots of space for short talks / late breaking speakers. Help us get the word out & come join us in 2025! FASEB events.faseb.org/event/11797f9e…

Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress nature.com/articles/s4159…

The claustrum getting some spotlight 👏Or an add for Colgate

In neurodegeneration, neurons release lipids that accumulate in glial LDs. In our latest spotlight article Trends Cell Biology, we highlight a study by Li et al. that reveals how the loss of neuronal AMPK activity increases lipid efflux, driving a proinflammatory state in microglia.

Congratulations to Maria Ioannou, assistant professor in the FoMD Department of Physiology, who is the 2024-25 recipient of the Martha Cook Piper Research Prize. This award recognizes Ioannou’s strong research record and outstanding promise as a researcher. Read about her

My first co-first author manuscript is out now in MBoC! 🥳Thanks to American Society for Cell Biology MBoC for selecting our image for the cover of the Oct 1 issue🤩 The Zanic Lab Vanderbilt School of Medicine Basic Sciences Vanderbilt Cell and Developmental Biology Vanderbilt Cell Imaging Shared Resource molbiolcell.org/doi/prev/20240…

AQLM 2025 is happening April 30-May 9th--applications due Dec 16th. Come join us for 10 days of awesome microscopy! #AQLM Marine Biological Laboratory (MBL)

Dare I say the claustrum is trending in Trends in Neurosciences?

Thrilled to preprint my postdoc work in the Maria Ioannou ! 🚀 Using live-cell and two-photon imaging, we reveal that Parkinson’s-linked glucosylceramide changes drive the formation and shedding of ectosomes, fueling α-synuclein spread. This pathway has broad implication in PD.

We've been studying mechanisms of resilience that protect lysosomes from damage and wrote a review on the topic. We consider lysosomal stress and damage on a spectrum; hopefully a useful concept😀. Snapshot below and Open Access here: embopress.org/doi/full/10.10…

Happy International Women’s Day! 🌎😄🧠💪 - from Lady GABA

Super excited to share this work!! Thank you to everyone who helped with the project!

Ever wanted a virtual assistant that you could show your #microscopy images to get help with visual understanding, hypothesis generation, and experiment design? I'm pleased my team contributed to this reasoning benchmark led by James Burgess (at ICLR 2025) to test these abilities using current MLLMs

I am beyond thrilled to co-organize this FASEB #LipidDroplet conference with Mike Henne_Lab in 2026! Check out the lineup and plan to participate - you do not want to miss this one!! #lipidtime