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Thrilled to share that my work is out in nature. Here, we introduce Peptide Predictor, a tool for identifying new bioactive peptides. Using this method, we discovered BRP, an anti-obesity peptide. Huge thanks to the SvenssonLab and all our collaborators! nature.com/articles/s4158…

If this holds in clinical trials, it could revolutionize cancer treatment and make it so much more accessible! Incredible finding 👏

Donald Trump is comedy gold! That he can so effortlessly and decisively say "transgender mice" instead of #transgenic mice & convince people that science is a waste of money is at the same time scary & hillarious!

Our group NNF Center for Basic Metabolic Research (CBMR) is now driven by an all women workforce (barring Kei), & we are incredibly fortunate to have these (multi)talented, hard working & generous women who support & elevate each other every day! Happy International Women's Day! #WomensDay2025

#InternationalWomensDay

Today marks the beginning of OpenRxiv, which replaces bioRxiv and medRxiv, the world's largest preprint platform for life and medical science openrxiv

Lab Sakamoto members at the Metabolism Day #MD25 NNF Center for Basic Metabolic Research (CBMR) Posters were presented by postdocs Joy & Jordana and by PhD students Maria, Hongling, Conchita & research assistant Costanza. #AMPK #TFEB #SIK bsky.app/profile/labsak…

The Sakamoto group members in action on Metabolism Day #MD25 , a 1 day international conference about energy control and metabolism organized by NNF Center for Basic Metabolic Research (CBMR) , now in its 7th successful year!

First time doing a X-tweetorial on our manuscript, be kind ! Our latest work in Nature Metabolism uncovers a striking role for glycogen accumulation in lung adenocarcinoma (LUAD) using spatial metabolomics & MALDI imaging. A thread 🧵 (1/)

Really excited for this! Lawrence Kazak, Jacqueline Beaudry, and Hoon-Ki Sung Lab put together an fantastic lineup!

Introducing blebbisomes! Cover art by Zachary Sanchez! #CellBiology Article: nature.com/articles/s4155…

The Lim Lab is recruiting PhD students or Postdoctoral Fellows to study the roles of 14-3-3zeta in #adipocytes or pancreatic #betacells. Projects are supported by CIHR , NSERC / CRSNG, or Diabetes Canada Please share or RT. Thanks! Centre de recherche du CHUM Université de Montréal Faculté de médecine

We are lucky to have incredible #diversity in our group where we learn about new #cultures, #languages, #traditions & most importantly, food! We did a potluck with traditional cuisines around the world & these scientists are not only brilliant, they have mad culinary skills too!

This study characterizes de-differentiated #FatCells (DFAT) from different fat depots, exploring their ability to re-differentiate, the impact of #HighFatDiet conditions, and their significance #invivo. #MetabolicHealth 👩‍🔬👨‍🔬Chinese Institute for Brain Research, Beijing Peking University 🔗sciencedirect.com/science/articl…

Excited to share that work from my PhD thesis is now available in Nature Metabolism! Here, we uncover a link between heme production, BCAA metabolism, and thermogenesis—implicating heme synthesis in #aging, #obesity, and #T2D. Link: nature.com/articles/s4225… A 🧵 (1/14)

Shocked to hear about the sudden passing of Prof. Gary Lopuschuk University of Alberta His contributions to the field of cardiovascular research is unmatched. It was my great pleasure to collaborate with him & his team while I was DalMedNB Truly a terrible loss! pediatrics.cmail20.com/t/d-e-sdltux-l…

After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology. Lately, I’ve focused on

Antibodies don't work. NLRP3 is by far the most studied inflammasome — yet <30% of commercial antibodies were specific. Only 4 of 14 tested antibodies detected NLRP3 specifically. Antibodies must be validated before use. Full report by YCharOS zenodo.org/records/116239…

When is a change in mitochondrial bioenergetics reflective of 'mitochondrial dysfunction' vs 'intentional reprogramming'? Here we present traditional vs alternative interpretations of mitochondrial responses to muscle disuse. physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

Can we feel our mitochondria? We feel pain (nociception), internal sensations (interoception), and even our immune system (immunoception) How does the brain monitor our energy status? In this preprint, we propose that the brain feels the balance of energy demand (burn rate)