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Our work describing the modulation of co-translational protein folding by rational design and ribosome engineering was published by Nature Communications nature.com/articles/s4146… That was a long journey! Thank you! Minkoo Ahn Alkistis Mitropoulou and JC group:) UCL Biosciences

🚨 So excited for our paper to finally be out Nature Chemistry. We use 19F #NMR to identify and study partially folded nascent chains that are stabilised by the #ribosome. Thanks to all my co-authors & John Christodoulou group! UCL Biosciences 🧲✨ nature.com/articles/s4155…

The danger is that with headlines everywhere blaring about protein structure being “solved”, funding for experimentalists and method developers will dry up. Problem is, it’s not TRULY solved until all the crucial details are right.

Cryo-EM of soft-landed β-galactosidase: Gas-phase and native structures are remarkably similar biorxiv.org/cgi/content/sh… #bioRxiv

Congratulations to all my wonderful colleagues and our superb students who made this happen. Very proud to work at such a magical place.

Excellent review of our understanding of the structure of proteins and the chemical forces that hold them together... As it was understood in 1939. Incredible how far we have come since then JD Bernal, Structure of Proteins doi.org/10.1038/143663…

Nature research paper: mRNA reading frame maintenance during eukaryotic ribosome translocation go.nature.com/3N4WX7X

I fully expected - & often predicted - the slow restoration of pre-Brexit positions on diminished terms & with reduced clout. But I confess I did not expect them to pretend they represented some sort of victory or achievement. I’ll never learn…

Ten days til the London NMR Forum restarts - 5pm Thursday 25th Jan The Francis Crick Institute. Don't forgot to register (free) at londonnmr.wordpress.com. We've also added a sign-up link for a new mailing list to keep up to date with upcoming meetings. #nmrchat #londonnmr

Congratulations, it is a very nice paper !

Nature research paper: Structural basis of ribosomal 30S subunit degradation by RNase R go.nature.com/48badzL

They partied , they bet on elections , they crashed the economy, they broke every public service, they destroyed integrity and honesty in public office , they paid their mates billions , they put their friends in the House of Lords, they gave their cronies knighthoods, they went

🚀 Excited to share our new paper on #cryoENsemble! A method that captures dynamic information from 3D cryo-EM maps using molecular dynamics simulations. 💻 Read more at Scientific Reports: nature.com/articles/s4159… #cryoEM #MolecularDynamics

Out now in nature! Our newest work using all-atom MD, 15N PREs and of course 19F NMR of ribosome-bound nascent proteins where we discover the unique thermodynamics of co-translational folding. #nmrchat UCL Biosciences

Do you like to be a part of our research, including development of NMR methods and advanced application ? Then join the UCL Biomolecular NMR Facility as a facility manager in the Division of Biosciences UCL Biosciences Apply below #NMRchat jobs.ac.uk/job/DIW124/bio…

Huge congrats 👏👏 to Rina Rosenzweig who has just been awarded this year’s NMR Community Founder's Medal for her truly impressive work on using advanced #nmr to elucidate the complex mechanisms of chaperones. Rosenzweig Lab

Happy to share our new preprint describing how #compchem can aid in 19F #NMR experimental design to study large complexes and proteins in cells - with co-first author Sammy Chan , Saifu Daya and John Christodoulou biorxiv.org/content/10.110… #NMRchat