Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases bit.ly/3GEisKB

In medicine, we don’t say “I love you”, we say “it’s not unreasonable” and I think that’s beautiful.

It is not inclusion if...

🧵regarding the 'right angle' clamp, including: why 'right angles' usually aren't actually 90° (which is a good thing), other problems with the name, why the original French name was cooler, what it's used for, and assorted other thoughts.

#OnlineFirst: Radiographic predictors of aneurysmal etiology in patients with aneurysmal pattern subarachnoid hemorrhage thejns.org/view/journals/…

🧵of 🧵 In the past, we've covered most of the commonly used sutures...today we'll go over Ethibond (polyester) sutures, which you may or may not be accustomed to to. As with the other suture 🧵, we'll go over properties, history, the kinds there are, and some of its uses. (1/ )

I don’t know when or how I learned that gtt means drip but I accept that it does.

Well, looks like ChatGPT can pass the USMLE now. (h/t Rian Kabir, MD) medrxiv.org/content/10.110…

On the history of 'palming' the needle holder: In 1973 Oschner noted that palming was widespread due to the influence of the trainees of Frederick Coller, surgery chief at U Michigan. Oschner's father then told him the real reason why Coller 'palmed' was that he had arthritis:

More than 21% of #neurosurgery residents are female now! We clearly have a ways to go, but that's more than double what it was when I started, so we're going the right direction! #WomenInMedicine #WomenInSurgery

Hungry for an easy way to remember aneurysm types? Think of them like different types of FRUIT: Saccular=focal outpouching like a GRAPE off a branch Fusiform=diffuse widening like a PEAR body Dissecting=BANANA w/the peel bulging out #meded #medtwitter #neurotwitter #radres

1/Does trying to remember inferior frontal gyrus anatomy leave you speechless? Do you get a Broca’s aphasia trying to name the parts? Here’s a #tweetorial to help you remember the #anatomy of this important region #medtwitter #meded #neurotwitter #neurorad #radtwitter #radres

Short 🧵(for people going into critical care) regarding when a tracheostomy tube is the same 'size' as its endotracheal tube counterpart, and when it is not. Warning: minutiae follows here...if you're not into critical care, get out now. (1/ )

Happy Match Eve to all the incoming neurosurgery residents! It’s a wild, wonderful ride!

So thrilled!! Would ya look at this crew?! 🧠💀

In medicine, anatomy is power. It helps diagnose & treat disease--but you must know it first! Posterior fossa perforator branches are key in #stroke. How many do you know? Here's a color coded map of perforators from each vessel,to help you branch out! #medtwitter #meded #neuro

Some said attending neurosurgeons didn’t exist (ok it was just me, I said that) but I found a lot of them at #AANS2023. Thank you for welcoming an ophthalmologist and confirming that it’s not the shunt. It never was.

Fascinating new preprint on bioRxiv tackles a whale of a question: Whales are huge. So why don’t they get a ton of cancers? biorxiv.org/content/10.110…

1/Does PTERYGOPALATINE FOSSA anatomy feel as confusing as its spelling? Does it seem to have as many openings as letters in its name? Let this #tweetorial on PPF #anatomy help you out #meded #medtwitter #FOAMed #FOAMrad #neurosurgery #neurology #neurorad #neurotwitter #radres

Oh you’re going to a teaching hospital in July? Well get ready… for the most compassionate care from extremely empathetic interns along with their vigilant supervising attendings. Hope you like open ended questions and doctors listening to you bc you’re gonna drown in it.