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Happy to share our new work in ⁦Nature Communications⁩. We report ACT-DC, a nanoparticle-boosted dendritic cell therapy that turns tumor into an effective vaccination site for in situ immunization. nature.com/articles/s4146…

I would like to share our team's invaluable study on the non-invasive mechanical control of CSF outflow via the meningeal and superficial cervical lymphatics!

📢Article now online Nature Cancer 'Skeletal muscle endothelial dysfunction through the activin A–PGC1α axis drives progression of cancer cachexia' ✏️By Young-Mee Kim, Jalees Rehman and colleagues 🔗nature.com/articles/s4301…

Excited to share our work with Mark Cookson and Payel Sen labs. We combine #SingleCell and #Nanopore sequencing to profile #RNA isoforms from young to geriatric mouse brains. We uncover #aging changes in transcription, processing, and splicing that also impact coding potential

Important new paper from the Teruyuki Sano lab on how miseducation of T-cells in the gut can lead to neurological damage via molecular mimicry: "Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation" in nature nature.com/articles/s4158…

Thrilled to share our study Immunity how a TB-vaccine (BCG) and a fungi fragment (b-glucan) synergistically train neutrophils against cancers A big shout out to Leonardo Jurado the entire team and collaborators Josefowicz Lab Ajitha Thanabalasuriar Eva Kaufmann authors.elsevier.com/a/1lJal_OR%7Ey…

Grateful for the thoughtful News and Views by Cancer Cachexia Society pioneers Teresa Zimmers and denis guttridge nature.com/articles/s4301… on our paper nature.com/articles/s4301… in Nature Cancer - highlights the importance of cross-disciplinary approaches to tackle #cancer #cachexia

Proud to share our new nature study: We developed the 1st NNMT inhibitor that reprograms cancer-associated fibroblasts, boosting immune response & stopping tumor growth in ovarian cancer models, especially when paired with immunotherapy. Lengyel Lab nature.com/articles/s4158…