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CONGRESS | #ASH22 James Blachly, Ohio State presented early results from a study of MS-553, a highly selective PKC β inhibitor. Enrolled pts had #CLL or #SLL and were heavily pretreated. MTD was not reached. 48% of pts achieved PR/PRL with MS-553 monotherapy. #lymsm #hematology

Merry Christmas to all, even the person who paged me for not 1 but 2 routine hem consults at 11:45p on Christmas Eve and 1:30 am Christmas morning

You would think for a $730 registration and $375 membership fee ASH could just let us watch the education spotlight videos from #ASH22 at our leisure.

Brian Shaffer Krishna Komanduri, MD, FASTCT ASH MEASURE data is coming - I heard Brian Shaffer MSKCC Lori Muffly Stanford University Elizabeth Krakow Fred Hutch Cancer Center Dr Salhotra and Amanda Blackmon City of Hope Chris Gibson Dana-Farber Alexandra Gomez A. Weill Cornell Leukemia James Blachly Ohio State Antonio Jimenez Jimenez UMiami Health System and other leaders are on the case!

Does anyone know the current policy of major oncology/hematology conferences regarding preprints? Especially for ASH. Submit before/with/after conference abstract? #leusm #BMTsm bioRxiv medRxiv

**100 years** of 24h of Le Mans today -- Vive la France! #24heuresdumans

🙌🏻🙌🏻

Anyone have a suggestion for a good iOS app to crop and deskew photos of slides? #ASH2023

GREAT WORK on folate role in hematopoietic development by briankrum1 presented as #ASH23 plenary scientific. 🙌🏻 I loved the first question which was a practical one: should we have BMT recipients supplement folate?

Now, which clinical investigator is going to step up and dedicate themselves to doing the confirmatory prospective RCT? Biomarker available. A chance to change clinical practice.

Menin inhibition will dramatically change the treatment of acute leukemia. We get first taste of this with KMT2A-r data on revumenib at #ASH23 LBA-5 ; can't wait for data on more drugs, new contexts, and combos 🚀 Great job Ibrahim Aldoss City of Hope !

I'm two time zones west of home and >no way< am i making it to midnight here, so happy New Years to all and see you in 2024 🫂 It's snowing tho so I'll wake up early to make fresh tracks ⛷️

entering 2024 with this energy

Private chemo infusion rooms are a net negative for patients

In IHIS (the medical record) they removed the quick access icon indicating patient is on research and replaced it with a leaving-AMA button 🙄

What an absolutely outstanding meeting thus far! I am blown away. Can’t wait for the next sessions—thank you #DAVAOnc MD Anderson Cancer Center Tapan Kadia James Blachly John F. DiPersio Lab

So, so important. I am stoked for the future of our field. Onward to new molecular subsets and combinations.

Rest easy, Sky King.