🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

🔍 Investigadores Descobrem o Que Impulsiona o #CancroÓsseo Agressivo 🦴 Coautorado por Jose Espejo Valle-Inclan ChampalimaudResearch durante o pós-doutoramento no EMBL-EBI. 📖Cell Artigo: cell.com/cell/fulltext/… 👀 Resumo: fchampalimaud.org/pt-pt/news/inv… 🎨 Karen Arnott

Now online! Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution dlvr.it/THMMjr

🗨️Jaume Mora, de Hospital Sant Joan de Déu Barcelona ES: "Este estudio, gracias al sofisticado análisis genómico de regiones múltiples de tumores y el análisis bioinformático asociado extremadamente complejo, ha permitido descifrar un puzle que parecía insondable" sciencemediacentre.es/describen-un-m…

‼️Fascinating work from Jose Espejo Valle-Inclan Isidro Cortes-Ciriano and colleagues 1⃣ #Chromothripsis drives tumor evolution in #osteosarcoma 2⃣A new mechanism, loss-translocation-amplification chromothripsis causes puntuated evolution in 50% ostesarcomas 3⃣LOH is a new predictive tool 👇👇

Enhorabuena al aragonés Isidro Cortes-Ciriano, a Jose Espejo Valle-Inclan y todo su equipo, por este importante trabajo que puede suponer nuevos avances en el tratamiento del cáncer. Como decía Noah Higón Bellver esta semana en La Revuelta: ‼️sin ciencia, sin investigación, no hay futuro.

A major driver of the bone cancer osteosarcoma has been discovered by a team led by Prof Adrienne Flanagan and Isidro Cortes-Ciriano EMBL-EBI providing insights that could help to predict cancer severity and response to treatment ucl.ac.uk/news/2025/jan/…

New research using data from the 100,000 Genomes Project is providing insights to help predict patient outcomes and improve the condition’s management. Many thanks to the participants for making this research possible. Find out more: genomicsengland.co.uk/news/researche…

‼️In November, we launched ASEICA-International. Now’s the time to join! 🚀 If you are a cancer researcher in Spain or abroad, this is for you! Sign up now using the QR code👇✨#ASEICAInternacional #CancerResearch #CareerOpportunity ASEICA

El #4F es #DíaMundialContraElCáncer Traemos este interesante artículo de Manuel Ansede que cuenta los avances en #investigación sobre el mecanismo del #osteosarcoma, un tumor de los huesos, que describen como terremoto en el #ADN, #chromothripsis, que provoca este cáncer

#ResearchWatch: aacrjournals.org/cdnews/news/21… Loss–Translocation–Amplification #Chromothripsis Drives #Osteosarcoma Evolution, a summary of the study by Jose Espejo Valle-Inclan, Solange De Noon, Adrienne Flanagan, Isidro Cortes-Ciriano, EMBL-EBI Wellcome Sanger Institute Genomics England UCL Cancer Institute

Introducing SAVANA, a tool to detect somatic structural variants and copy number aberrations from long-read sequencing data with high sensitivity and specificity. nature.com/articles/s4159…

Thrilled to see #SAVANA out in Nature Methods🥳 SAVANA detects haplotype-resolved somatic SVs and copy number aberrations (SCNAs) and infers tumour purity & ploidy in clinical samples using long-read sequencing with or WITHOUT a matched germline control 👇nature.com/articles/s4159…

Long-read 🧬sequencing reveals hidden cancer mutations, but existing tools often produce false positives. SAVANA is a machine learning algorithm trained on cancer genomes, built to make analysis faster and clinically reliable. ebi.ac.uk/about/news/res… #CancerResearch