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The "ChatGPT moment" for biology proceeds to unfold as Profluent announces proseLM, a new method which incorporates structural and functional context to protein language models for precise and steerable protein design. Ali Madani Jeff Ruffolo 1/ genengnews.com/topics/artific…

Excited to share my summer internship project Profluent! We used adapters to finetune protein language models for conditional generation of enzymes with desired functions and taxonomies, called ProCALM. Aadyot Bhatnagar Jeff Ruffolo Ali Madani Paper: arxiv.org/abs/2410.03634

Finetuned protein language models for conditional generation of enzymes with desired functions and taxonomies. Jason Yang Aadyot Bhatnagar Jeff Ruffolo Ali Madani

I’ll be in Vancouver for NeurIPS December 13-16, reach out if you’re interested in protein language models, genome editor / antibody design, or any of the other cool stuff we’re doing Profluent!

1/ Today we announced new research in the ability of AI models to precisely modulate protein-DNA interactions without iterative lab screening. 🧵

What could scaling unlock for biology? Introducing ProGen3- our next AI foundation models for protein generation. We develop compute-optimal scaling laws up to 46B parameters on 1.5T tokens with real evidence in the wet lab. +we solve a new set of challenges for drug discovery

What if the same AI advancements that have transformed ChatGPT could be replicated in biology? Enter ProGen3, our latest foundation model suite for protein generation.