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I use #gganimate in #Rstats to animate cell cycle genes from our 10k gene MERFISH PNAS paper. It's like a #singlecell loading icon! Code: jef.works/blog/2020/12/2… Paper: pnas.org/content/116/39… 🥂 #BioInformatics #DataScience #DataVisualization #dataviz #bioviz #funwithcode

Curious to hear from people in different fields: Which findings / methods / developments in your discipline have intrigued you the most in the past 5 years and why? OpenAcademics #AcademicTwitter #AcademicChatter #phdvoice #phdlife

Very proud to present our work "Spatiotemporal dissection of the cell cycle with single-cell proteogenomics” in @nature today. A great (and long) team effort led by Diana Anthony Cesnik, w Human Protein Atlas. A thread... #cellatlas #cellcycle go.nature.com/3sq8sKE

Pleased to present 'tricycle', a new R package for rapid, accurate, and scalable estimation of cell cycle position for scRNA-Seq using transfer learning. A joint project from our lab and the lab of @KasperDHansen. doi.org/10.1101/2021.0…

Delighted to share my lab’s jdavieslab first big paper in nature! We’ve developed a new 3C technique called Micro Capture-C that can generate base pair resolution 3C data nature.com/articles/s4158…

Our latest paper (in Nature Communications) characterises a mongenic anemia causing variant. We show how it creates a de novo promoter that acts as an enhancer-blocker. #3Dgenome #generegulation nature.com/articles/s4146…

Delighted to see Andrew King et al.'s characterization of primitive alpha globin regulation come out in Nature Communications today. Including a beautiful example of what you can do with James Davies new MCC method (described in @nature last month). nature.com/articles/s4146…

A recent publication in Current Biology examines asymmetric nuclear division in Drosophila neural stem cells and finds that the daughter nuclei differ in chromatin organisation, envelope composition and size. Chantal Roubinet Ian White Buzz Baum's Lab cell.com/current-biolog…

Scientists are identifying characteristics that might make some rare cancer cells, called cycling persister cells, resistant to drug treatment. The results could help researchers design therapies to delay or ultimately prevent disease recurrence. broad.io/PersisterCells

Working with jdavieslab we have identified the likely gene at 3p21.31 responsible for increased risk of COVID-19 respiratory failure. Published in Nature Genetics today! nature.com/articles/s4158…

Really excited to share our latest paper... fantastic collaboration with Marieke Oudelaar where we developed tiled Micro Capture-C to generate Hi-C like plots at 20bp resolution. Turns out there are nanoscale TADs inside enhancers! nature.com/articles/s4146…

Thank you all the participants! It was very nice and productive time with guys at #EMBODevTempo ! Definitely catch up with you soon!❤️

Giving a talk and discussing my work on transcriptional regulation of genes throughout the cell cycle at Keystone Symposia #KSChromatin23 was such a cool experience. Really grateful to have had this opportunity!

It's great to see the project I worked on for my Master's Thesis at KU Leuven out as a preprint. Congrats to everyone who has been involved in this work!

How do distal enhancers control transcription dynamics in living cells? Check out our latest work published in Molecular Cell!! We show that the dynamic assembly and disassembly of TF clusters at enhancers are a major source of transcriptional bursting. cell.com/molecular-cell…

Our second session is off to a flying start with a deep dive into gene regulation in the cell cycle delivered by Jennifer Herrmann Co-supervised by Jim R. Hughes (Hughes Group) and Rob Beagrie (Centre for Human Genetics)

Congratulations to Lauren (Lauren Murphy), Patrick, Jennifer (Jennifer Herrmann), and Anna, who have been shortlisted for the Ita Askonas Medal 🏅 and will give talks at #WIMMday2023 for the chance to win a prize of £500! 🎉