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The missing piece in the bacterial #ESCRT-III story.. #Vipp1 forms dynamic spiral filaments on membrane! Spirals are springs that drive 3D ring formation in the spiral centre! 😎😵‍💫 Wonderful collaboration with A_Colom Roux Lab… 1/2 biorxiv.org/content/10.110…

Excited to share the first paper from our lab is out as a preprint! Joshua Huffines established a dual-species culture model to investigate S. aureus-Corynebacterium interactions on nasal cells & how temperature influences bacterial persistence & cytotoxicity

The #cryoEM research centers UW–Madison Biochem are recruiting! We seek to hire an #administrative #assistant to join our team. We are looking for someone who has a passion for science, organization, communications, and outreach. Take a look! DM & RT! jobs.wisc.edu/jobs/administr…

It's phenomenal. We use it every day to guess unknown pili sequences. For our recent 3.5 Å pilus structure in bioRxiv, the predicted sequence is 56% to the correct protein (using the default parameter). Our lab record is 85% correctness for a 2.4Å novel pilus structure. 🍷❄️

We have received a lot of requests for help with making streptavidin affinity grids. We are happy to finally share our protocol for robust in-house fabrication of streptavidin affinity grids. Stay tuned for the accompanying video that is coming soon! app.jove.com/t/66197/strept…

Excited to finally share this final product! Analysis of NIH K99/R00 awards and the career progression of awardees elifesciences.org/articles/88984 There is bias in faculty hiring networks! bottom line.

wow our Geo nanowire structures were there! They were drawn in such an elegant way!! 🥳🤩🙌

Check out our new cryo-EM preprint on bacterial flagellar outer domain diversity! No clue who'll see this due to Twitter's new algorithm. Important points: most work was done by rotation students, and collaborating with the Wu lab is great. HWU-OHSUSoD 🦠biorxiv.org/content/10.110…

I guess our research future is bright... Vincent Conticello I didn't see this coming #3BodyProblem 🍷👽

🔬👩‍🔬 Exciting news! I'll soon start my lab Van Andel Institute (VAI) to research molecular mechanisms in Neurodegenerative diseases. 🧠💡 Now recruiting postdocs to join our dynamic research team! Email me if you're interested! #Postdoc #CryoEM #Neuroscience #ResearchOpportunity

Thrilled to announce AlphaFold 3 which can predict the structures and interactions of nearly all of life’s molecules with state-of-the-art accuracy including proteins, DNA and RNA. Biology is a complex dynamical system so modeling interactions is crucial blog.google/technology/ai/…

Our Manual Plunge Cooler and Precision Ethane Cryostat system for Cryo-EM are now available - Designed to make your cryo-EM sample vitrification workflow efficient and successful at a reduced cost - Learn more zurl.co/RoNE Video zurl.co/05n9 #cryoem

🚨 We've updated the glycan structure database on GlycoShape (glycoshape.org)! You can now search through and rebuild glycoproteins with 453 unique glycans 🥳 Glycans are now primarily listed by their GlyTouCan IDs Gly Kiyoko Kinoshita 🎉 #glycotime

Thank you Fengbin (Jerry) Wang Fengbin Wang (Jerry) for inviting me to speak at UAB_Biochem and meet Gino Cingolani Cingolani Lab, Laura Volpicelli-Daley Laura Volpicelli, Lindsay Rizzardi Lindsay Rizzardi, PhD, Peter Prevelige, Matthew Renfrow, Shu Chen, Louise Chow, and Tom Broker.

Researchers led by Phil Shuaiqi Guo, Jun Liu Lab, Lori L. Burrows report the structure of the Pseudomonas aeruginosa T4P suggesting the localization and role of its tip adhesin, PilY1. nature.com/articles/s4146…

Fengbin Wang (Jerry) @mkrupovic HWU-OHSUSoD used cryo-EM to determine the structures of three bacterial flagellar filaments, showing distinct outer domains. nature.com/articles/s4146…

Our study on how the human MCM2-7 helicase is loaded onto replication origins 🧬 is now online nature! 🎉 Our findings reveal that unlike in yeast, human MCM loading does not require ORC6 and can occur through multiple pathways. Read more here: rdcu.be/d1F6S

1/ Thrilled to announce Dr. Elizabeth Wright from UW–Madison Biochem as the inaugural winner of the June Almeida Award for #cryoem! 🎉Elizabeth’s pioneering work in both cryo-ET methods and structural virology made her a perfect fit for this award. Congrats, Elizabeth Wright! ❄️🔬

Donor Strand Complementation and Calcium Ion Coordination Drive the Chaperone-free Polymerization of Archaeal Cannulae biorxiv.org/content/10.110… Happy that the preprint is now published. Great collaboration with fantastic colleagues. conticellolab Emory Chemistry

Another wonderful collaboration with Alan Brown lab. The Zhang lab together with Polina Lishko lab (co-first author Qingwei Niu) contribute the doublet microtubule structure from Crithidia fasciculata, a model organism that infects mosquitoes. science.org/doi/10.1126/sc…