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Now Online Dynamics of DNA replication speeds in single cells dlvr.it/TCs74X

Take a look at our latest Tools of the Trade article, written by Jeroen van den Berg on work done in the Alexander van Oudenaarden lab! See the original paper Nature Methods: nature.com/articles/s4159…

Wow! Super humbling to see our method being presented at a meeting I could not visit! Alexander van Oudenaarden vincentvB! Thanks a lot @FMattiroli and Anja Groth 🇺🇦 👏 🥳

I’m so thrilled to share my first first-author pre-print! 💪🎉🥳 This was an amazing collaborative work from Nitika Taneja, Andrés Aguilera and @lugerlab! How do #chromatinremodelers, #Rloops and mutations in #cancer correlate? A small 🧵below for you! biorxiv.org/content/10.110…

Now online! In vivo DNA replication dynamics unveil aging-dependent replication stress dlvr.it/TDMNkz

Outstanding science and high spirits at CSHL Epigenetics & Chromatin meeting #cshlepich24 Berger Lab The Nogales Lab Anne Ferguson-Smith Yael David Peggy Goodell Asifa Akhtar Geneviève Almouzni Narlikar, Luger, Jabado

Did you know that DNA polymerase κ plays dual roles in translesion DNA synthesis? Julien Duxin’s latest NatureStructMolBiol article explores its catalytic and noncatalytic functions in bypassing DNA lesions. Check it out here: rdcu.be/dUFTk Kudos to the amazing team! 👏

Great work Stefano Giustino Manzo !! 🎉 Congrats to all the authors

Excited to start this new endeavor! Thanks to Danmarks Grundforskningsfond for selecting our application for a center of excellence and to the Danish Cancer Institute for welcoming us Kræftens Bekæmpelse

I'm delighted to have received the award for best presentation at the 10th NECO. It was a fantastic experience with exceptional people. CenGEM Evi Soutoglou Diana Rubio

Job alert! Do you know a postdoc candidate that loves microscopy and wants to visualize how cells repair their DNA, please forward them this opportunity: lumc.nl/en/about-lumc/…

Cost of having DNA methylation: DNA replication by DNA polymerase epsilon is a source of C to T mutations in CpGs, especially methylated ones. This expands our understanding of one of the most widespread endogenous mutational mechanisms. nature.com/articles/s4158…

Happy to share latest work from the lab! nature.com/articles/s4146…

Researchers from the Mattiroli group discovered that DNA packaging in cells can directly impact the speed of DNA copying during cell division. The packaging sends signals through an unusual pathway, affecting the cell’s ability to divide and grow. More: hubrecht.eu/dna-packaging-…

Acute multi-level response to defective de novo chromatin assembly in S-phase (Dreyer et al., 2024) cell.com/molecular-cell…

Very interesting findings by the CAF-1 degron system! Slow replication reminds me of early mouse embryos. Acute multi-level response to defective de novo chromatin assembly in S-phase: Molecular Cell cell.com/molecular-cell…

Great to see this work finally out in the open! It was a lot of fun to collaborate with the lab of @FMattiroli

It was an absolute blast to write this Novo Nordisk Foundation grant together with my long-time friend Leonie Alimojanid and to now to have it funded for 2M EUR🤯. Many thanks to Alexander van Oudenaarden and Anja Groth 🇺🇦 for their unwavering support and invaluable input! Exciting things to come 🎆🎆🎆

Do not miss out on this webinar on Bio-protocol to see what we have been up to in quantifiying single cell DNA replication dynamics using scEdU-seq ! 🚀 Register now! bio-protocol.org/webinar/detail…

Happy to share this concise review and outlook for single-cell sequencing methods to unravel cell biology of the nucleus! Big shoutout to my friend and former colleague Peter Zeller for sharing the work! sciencedirect.com/science/articl…