EISG Helsinki 2024 | University of Helsinki. Next instalment! Outstanding speakers and an exciting venue. helsinki.fi/en/conferences…

Is binarization of scATAC-seq data really necessary? The conclusion from our analysis is that a quantitative treatment is in fact beneficial. Now out in Nature Methods! gagneurlab Fabian Theis nature.com/articles/s4159… Many additions since the preprint 👇(1/n)

Exciting news! Our latest research on "Cell type directed design of synthetic enhancers" has been published in nature. We've harnessed deep learning to design enhancers with cell-type specificity. Find our paper here: nature.com/articles/s4158…. Highlights below: [1/n]

Andreas Møller Jesper Madsen present JOINTLY, a hybrid linear and non-linear NMF-based algorithm, providing interpretable and robust cell clustering across batches against over-integration. Nature Communications #singlecell #BiotechNatureComms nature.com/articles/s4146…

Very excited to share a new work on AUPRC, AUROC, and class imbalance: arxiv.org/abs/2401.06091 The short of it? Despite widespread belief, AUPRC is not superior to AUROC under general class imbalance and it can exacerbate biases towards subpopulations with higher prevalence.

Extremely excited to open the registration for the 2nd Annual Variant to Function Symposium hosted by the Novo Nordisk Foundation Center Broad Institute co-Chaired by Melina Claussnitzer, Ph.D.. A stellar (!!) lineup of speakers & virtual+physical attendance. Please share! broadinstitute.swoogo.com/V2F

The commentary I wrote is now live at Nature Biotech: nature.com/articles/s4158… (free version rdcu.be/dwSSy).

🧵: How do you design a network that can optimize (edit, transform, ...) the weights of another neural network? Our latest answer to that question: *Universal* Neural Functionals (UNFs) that can process the weights of *any* deep architecture.

Our watching party getting ready to dive into what will sure be an excellent talk by Melina Claussnitzer, Ph.D. 🤯 at the V2F symposium hosted by Novo Nordisk Foundation Center Broad Institute

Honesty is the best policy ncbi.nlm.nih.gov/pmc/articles/P…

Currently at #EISG2024 in Helsinki 🧬 I presented my PhD research, conducted in Susanne Mandrup ‘s lab and co-supervised by Jesper Madsen at Functional Genomics & Metabolism Research Unit SDU Science , in a poster session. Last photo by Hazem Ibrahim - who has posted more photos of the conference. Check them out!

New from us! We found that targeting mitochondrial programming promoted the formation and maturation of stem cell-derived beta cells. Mitos - more than a powerhouse! #T1D biorxiv.org/content/10.110…