
Jingwen Guan
@jingwen_guan
ID: 1309630191665164288
25-09-2020 23:05:52
9 Tweet
17 Followers
9 Following


I am very thankful for the fantastic post-docs that bring their diverse talents and backgrounds to our group! Nicole Marino, Shweta Karambelkar, Balint Bálint Csörgő Jingwen Guan, Yuping Li (Yuping Li), and Sukrit Silas (incl former: B. Rauch, S. Govindarajan)! #ucsfNPAW #NPAW2020


Delighted to share our latest preprint: the largest analysis assessing the contribution of rare genetic variants to the risk of depression, based on the exomes from 320,356 UK Biobank participants medrxiv.org/content/10.110…

Here, Jingwen Guan presents a new way to engineer phage genomes, using Cas13a + an Acr protein! We developed this because our favorite jumbo phage, phiKZ had no genetic tools. We are now using this to understand the jumbo phage secrets. short🧵biorxiv.org/content/10.110…



Does JukA sense ejected proteins? In phage head, phiKZ genome is wrapped around a proteinaceous inner body (IB) structure. It is unclear if IB proteins are ejected with phiKZ genome. Via fluorescence tagging, Jingwen Guan showed that 4 IB proteins are ejected into host. 11/n

