P. vulgatus quiets C. difficile Jordy Evan Sulaiman Venturelli lab UW–Madison Biochem show C. difficile exhibits coexistence, instability or exclusion in gut communities. C. difficile+P. vulgatus leads to mutants that alter C. difficile’s metabolic niche & reduce disease cell.com/cell-host-micr…

We found that many bacterial species use exogenous peptidoglycan fragments - released by lysis of neighboring cells - as a general danger signal, triggering a danger response that protects bacteria against many dangers: biofilm formation. Details👇: nature.com/articles/s4156…

🧵How does being a #vegan, #vegetarian or omnivore impact your gut #microbiome? Find out in our new paper on gut microbiome signatures of vegan, vegetarian & omnivore diets & associated health outcomes across 21,561 individuals in Nature Microbiology!🎉 1/10 nature.com/articles/s4156…

1/ Excited to share our latest work, just published in Nature Chemical Biology! We demonstrate how population-level gene regulation can be dynamically controlled and amplified using programmable gene transfer. Duke Center for Quantitative Biodesign Duke Biomedical Engineering Link to paper: doi.org/10.1038/s41589…

Discovery of a family of bile acid-methylcysteamines nature Cornell University @group_Schroeder #activitymetabolomics A nuanced interplay between host and microbiota in regulating bile acid signaling pathways through FXR with a new target for metabolic disorders doi.org/10.1038/s41586…

Today we report a compendium of human gut microbiomes with >168,000 samples We discovered distinct microbiome patterns across the globe, and show we can predict where a person lives just from their gut bacteria Now out in Cell cell.com/cell/fulltext/…

Today I learnt that there are 3 different types of hunger 📸: nejm.org/doi/full/10.10…

How our gut microbiome regulates sugar preference nature.com/articles/s4156…

New paper from the lab out today on Akkermansia muciniphila and how it breaks down host glycans! IMIBirmingham College of Medicine and Health (UoB) Very proud of my group, especially Cassie Bakshani who did an amazing job. Nature Microbiology nature.com/articles/s4156…

Diverse gut microbiomes protect against pathogens by blocking nutrient access, according to a 2023 Science study. The findings highlight why #microbiome diversity is important to human health. Learn more in this #SciencePerspective: scim.ag/3WGid8Z #ScienceMagArchives

Fiber fine tunes MHC to impact CDI Low-fiber diet worsens C. difficile infection by increasing MHC-II in colonic epithelium, promoting pathogenic CD4+IELs. Acetate from fibers enhances ILC3-derived IL-22, suppressing MHC-II expression The Colonna Lab cell.com/cell-host-micr…

Out today, Cell Host & Microbe! Microbiomes have many benefits, but they are also often incredibly diverse and variable. This makes them hard to understand and even harder to engineer. In our new review, we argue that the key may lie in microbial metabolism! sciencedirect.com/science/articl…

Metabolic ecology of microbiomes: Nutrient competition, host benefits, and community engineering Review by Erik Bakkeren, Vit Piskovsky, and Kevin R. Foster cell.com/cell-host-micr…

Review Nature Immunology The role of gut microbial metabolites in the T cell lifecycle nature.com/articles/s4159…