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Applications for the Harry Smith Vacation Studentship are open. A limited number of awards are available to enable undergraduates to work on microbiological research projects during their summer vacation. Deadline: 20 Feb 2025 23:59 GMT microb.io/2Gztpzy

Some interesting PhD projects here. Good teams with excellent track record of supervision.

#MicrobiologyMonday: Do probiotics spread antimicrobial resistance (AMR)? Streptomycin-resistant probiotics can transfer resistance to other bacteria when co-incubated on intestinal cells. The the fully story in Microbiology Spectrum: journals.asm.org/doi/10.1128/sp…

OUT NOW - Streptomyces secretes a siderophore that sensitizes competitor bacteria to phage infection nature.com/articles/s4156…

I'm excited to announce our latest publication! We teamed up with Karthik Hullahalli to barcode Klebsiella and ask basic questions about bacteremia pathogenesis: 1) how are bacteria shared between sites and 2) which host and bacterial factors influence dynamics? nature.com/articles/s4146…

New paper alert! Fitness benefits of carriage of an AMR plasmid, beyond antibiotic resistance! Microbiology Society microbiologyresearch.org/content/journa…

Klebsiella pneumoniae emerging anti-immunology paradigms: from stealth to evasion By Joana Sá-Pessoa (Joana Sa Pessoa), Ricardo Calderón-González, Alix Lee (Alix Lee) & José Bengoechea (Josebengoechea) dlvr.it/THj5Fv

New pre print! We establish an ex vivo blood vessel model to investigate the effect of infection on vascular physiology in real time. We show Klebsiella inhibits vasodilation in a T6SS-dependent manner by targeting eNOs. Superb work by Safi Rehman shorturl.at/5v4JE

A great collaboration with Dr. Jason Harris at Harvard Medical School! This is the first in-depth study of the immune response of patients with Klebsiella bacteremia. Antibody responses in Klebsiella pneumoniae bloodstream infection - The Lancet Microbe thelancet.com/journals/lanmi…

Vaccines are crucial in the fight against AMR. They help prevent drug-sensitive and drug-resistant pathogen infections, minimising the use and misuse of antimicrobials. Learn more on our roadmap for tackling AMR - microb.io/RoadMapTacklin…

AI-based imaging of zebrafish Position with Mostowy Lab Matthew Fuchter James Briscoe jobs.lshtm.ac.uk/Vacancy.aspx?r…

Delighted to share our last pre print -this one close to my heart- We set to define the rules of lipid A associated with virulence by interrogating the genus Yersinia. biorxiv.org/content/10.110…

#EveryCellIsAnImmuneCell! Yifat Merbl lab Karin Goldberg &co show nature that antimicrobial peptides are produced in a cell-autonomous manner by e.g. lung epithelial cells via proteasome degradation of host proteins, protecting against pseudomonas infections! nature.com/articles/s4158…

Prof. Josebengoechea revealling the insights on Klebsiella interactions with macrophages at the opening ceremony of the #AdvMicro2025 😊

New role for macrophages in Shigella infection control Margarida Gomes @DBrokatzky London School of Hygiene & Tropical Medicine Cell Reports cell.com/cell-reports/f…

💷 £2.2M to uncover the hidden life of a killer microbe 🦠🔬 Researchers London School of Hygiene & Tropical Medicine, funded by Medical Research Council, will lead a 5-year study into Klebsiella pneumoniae, a major drug-resistant superbug that silently colonises the guts of billions worldwide. Read more 👉 bit.ly/4mNSreh

This should be required reading by all graduate students and postdocs | A brief guide to statistical analysis of grouped data in preclinical research nature.com/articles/s4225…

Klebsiella pneumoniae remodels its Kdo2-lipid A in a TLR4-dependent manner to adapt to the macrophage intracellular environment | bioRxiv New pre print of the lab going deep into Klebsiella-macrophage interface. Superb work led by PhD student Toby Leigh Bartholomew

Delighted to have started my tenure as an editor for mBio journals.asm.org/journal/mbio handling papers on Streptomyces, natural product evolution and biosynthesis, experimental evolution, bacteriophage resistance, Corynebacterium and engineering biology

If anyone needs a clear explanation of how to do standardised antibiotic susceptibility testing (MICs) properly then I highly recommend this article nature.com/articles/s4425…