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📢Check out our latest work on how the #NOTCH3 pathway induces #supravalvular #aortic #stenosis jci.org/articles/view/…. Congratulations to Dr. Jui Dave and everyone who contributed to this work👏👏👏. Journal of Clinical Investigation Yale CVRC #CardioTwitter American Heart Association

The amazing aorta! #medial_layers #vascular_wall #elastin #smoothmusclecells #epigenetics #development #FluorescenceFriday👍 #myfirstTweet😊😊😊

Postdoctoral fellow @JuiMDave aims to unravel the cellular and molecular mechanisms of cardiovascular disorders. She is the first author of a recent Developmental Cell study: buff.ly/3IifskM Yale School of Medicine Yale Internal Medicine DanielGreifLab Yale CVRC

Beautiful elastin fibers 🥰 #aorta #elastin #blood_vessel #vascular_wall #media #smoothmusclecells #development #blood #heart #FluorescenceFriday 🌈

A study by Jui Dave from the DanielGreifLab has identified the role of Notch3 in vascular development. In a laboratory setting, treatment with a pharmacological inhibitor or the genetic deletion of Notch3 has a restorative effect on the aortic wall. buff.ly/3370qiN Yale School of Medicine

Thank you Yale News for highlighting our work! Yale Internal Medicine Yale Cardiology Yale CVRC DanielGreifLab yaledailynews.com/blog/2022/02/1…

The JAGGED1/NOTCH3 pathway induces pathological aortic changes in elastin-deficient models: buff.ly/3K5rfDM DanielGreifLab Kathleen Martin Jui Dave Lina Ntokou Seema Mital Yale CVRC Yale Internal Medicine #VascularBiology

Congratulations to Raja Chakraborty on this exciting story and to all our wonderful collaborators! Jui Dave DanielGreifLab Yale CVRC Yale Cardiology

Jui Dave, PhD, investigates potential therapeutic targets for obstructive arterial diseases, including supravalvular aortic #stenosis DanielGreifLab. Congratulations Jui Dave on your Career Development Award from AHA Science. buff.ly/3Pge6d4 Yale School of Medicine Yale Internal Medicine

Angiogenesis ❤️

👏Congratulations Dr. Inamul Kabir and colleagues for the latest article Nature Aging! "The #age of #bone marrow dictates the #clonality of smooth muscle-derived cells in #atherosclerotic #plaques" is now published👉 nature.com/articles/s4358…

📢📢📢 Publication alert! 🧠🔬🧑‍🔬 Dave et al. identify that repression of Angiopoetin-2 via TGFb pathway in #brain pericytes is indispensable for the blood-brain-barrier development! Kathleen Martin DanielGreifLab Yale CVRC Junichi Saito, MD, PhD Lina Ntokou Yale School of Medicine ahajournals.org/doi/abs/10.116…

#STROKE #OriginalResearch: Jui Dave et al. discover that the TGFβ pathway represses angiopoietin-2 in brain pericytes during development and identify pericyte-derived angiopoietin-2 as a target for germinal matrix hemorrhage. #AHAJournals ahajournals.org/doi/full/10.11…