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IRIS trial at #ESOC2025 shows promise for IL-6 receptor blocker tocilizumab as adjunct to EVT in acute ischemic stroke. Significant infarct volume reduction with favorable safety profile. A potential new step in neuroprotection - larger trials needed! #Stroke #Neuroprotection

Intrasaccular Treatment of Intracranial Aneurysms: A Comprehensive Review pmc.ncbi.nlm.nih.gov/articles/PMC11…

Wondering how to find the right mentor? Or mentoring mentees? Join @hopkinsNCCU division chief Dr. Suarez and co-panelists Dr. Wahlster, Dan Harrison, MD at this SCCM roundtable on navigating mentor-mentee relationships! Co-moderated by our own Vishank Shah, MD and Dr. Sahar Zafar!

For #StrokeAwarenessMonth, I’m joining SVIN #AllHandsIn Challenge. I tried putting on my white coat with my non-dominant hand and I couldn’t even finish. This is just a glimpse of what stroke survivors may face every day. #BEFAST Johns Hopkins Neurosciences Critical Care Johns Hopkins Medicine

Every 10 mg/dL ⬇️ in LDL for patients with ICAD stroke has 9% ⬇️ rates of recurrent stroke or MI. this theoretical framework suggests that PCSK9i can help achieve this. We need PCSK-9i trials in ICAD Jim Siegler (@jimsieglermd.bsky.social now) Tareq Kass-Hout Malik Ghannam Seemant Chaturvedi neurology.org/doi/10.1212/WN…

Intracranial aneurysms are common, and the risk of rupture is influenced by size, location, morphology, and factors such as hypertension, smoking, and family history. Management options and risks are discussed. Read the Clinical Practice article “Unruptured Intracranial

It is getting harder and harder to justify intensive BP lowering after thrombolysis or thrombectomy. In this secondary analysis of ENCHANTED (thrombolysis) no decreased edema for SBP 130-140 compared to < 180. Stroke AHA/ASA ahajournals.org/doi/full/10.11…

Neuroinflammation across neurological diseases | Science science.org/doi/10.1126/sc…

New data in LVO #stroke: Language improves > motor fxn after EVT/tPA. 🧠 Lang Δ +29.8% vs 💪 +12.4% EVT > tPA > no tx Cortical fxns more salvageable NIHSS may miss subtle lang gains 💬 Aphasia may recover more than paresis nature.com/articles/s4159…

Subcostal echocardiographic assessment of tricuspid annular kick (SEATAK): A novel independent predictor of 30-day mortality in patients with acute pulmonary embolism - PubMed pubmed.ncbi.nlm.nih.gov/36088580/

Absent pupillary reactivity does not preclude good outcome after #OHCA. Among those with absent reactivity, pupil dilatation (>4mm) suggests increased chance of progressing to brain death. Yale Neurocritical Care Resuscitation sciencedirect.com/science/articl…

Statin use was significantly associated with a reduced risk of SAH. ahajournals.org/doi/10.1161/ST…

Connectivity-based analyses implicated disruption of large-scale brain networks in the development of depressive symptoms. ahajournals.org/doi/10.1161/ST…

Difficult Airway Management in the Intensive Care Unit: A Narrative Review of Algorithms and Strategies CCR Journal Watch - tracking the critical care literature daily criticalcarereviews.com/latest-evidenc…

Gabapentin prescription in adults with chronic low back pain is associated with increased risk of dementia and cognitive impairment, particularly in non-elderly adults. Physicians should monitor cognitive outcomes in patients prescribed gabapentin. rapm.bmj.com/content/early/…

In this real world study of ESUS patients with AIS, anticoagulation was found to be associated with a reduction in recurrent stroke, as opposed to anti-platelet therapy, among those with left ventricular wall motion abnormalities neurology.org/doi/10.1212/WN…

Symptomatic Nonstenotic Carotids: A Topical Review | Stroke ahajournals.org/doi/10.1161/ST…

Embolic Stroke of Undetermined Source and Symptomatic Nonstenotic Carotid Disease | Stroke ahajournals.org/doi/10.1161/ST…