So many poster awards for our Morningside Graduate School of Biomedical Sciences students at #OTS2023! Congrats, Samantha Sarli, PhD (Jon Watts; 3 yrs in a row!!), Juli Buchwald (2yrs in a row), Ted Carrigan-Broda, Sam Hildebrand, Valeria Rivera (KhvorovaLab), & Rachael Miller (Aronin lab; 2yrs in a row)! 🥳

So many emotions. On one hand, I'm glad that the publishers of my fifth-grader's math textbook decided that chemistry was the best example of "modeling real life" to put on their cover. But could they not have talked to an actual chemist about the nature of bonding in NaCl first?

Original Research: In Vivo Prime Editing by Lipid Nanoparticle Co-Delivery of Chemically Modified pegRNA and Prime Editor mRNA ErikSontheimerLab Jon Watts liebertpub.com/doi/10.1089/ge…

Just out: our new genome editing fluorescent reporter mouse is compatible with multiple Cas nucleases and PAM sequences, and reports on both nuclease and prime editing. With ErikSontheimerLab and Wen Xue.

Erik Sontheimer, PhD; Jonathan Watts, PhD; and Scot Wolfe, PhD, have received $2.3 million from the Rett Syndrome Research Trust to target particular mutations in the Rett syndrome patient population: brnw.ch/21wHyVM #AdvancingTogether ErikSontheimerLab Jon Watts RSRT

Read more about it: UMass Chan studies selected for STAT Madness umassmed.edu/news/news-arch…

Watts lab research was selected to compete in STAT Madness again this year! This time the featured research is our collaboration with Joel Richter's lab, building on their key insight that splice-switching ASOs may be therapeutic for Fragile X. Vote here: statnews.com/feature/stat-m…

#newscience alert in @naturecomms ! How can you make Nme2Cas9 editing Harder-Better-Faster-Stronger? Check it out! pubmed.ncbi.nlm.nih.gov/38368418/

Congrats to SchaferLabUMassChan on this well deserved award!

In the latest paper from senior PhD student Samantha Sarli, PhD, we compare the activity profile of conjugated and unconjugated ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo. Amphiphilic lipids help drive safe uptake! Online now at NAR: academic.oup.com/nar/article/do…

Are oligonucleotides that are chemically optimized for normal brain also active in glioblastoma brain tumors? 👇 Hassan Fakih, Ph.D. Jon Watts

Loving Sudhir Agrawal's cover art for Nucleic Acid Therapeutics, cleverly reflecting the decades of work that have brought our field to its current state!

Congratulations Phillip Zamore of UMass Chan Medical School, newly inducted #NASmember! #NAS161 #genetics #medicine

Congratulations to the newly minted Dr. Samantha Sarli, PhD for passing her thesis defense RNA Therapeutics Institute UMass Chan Medical School with a great defense talk.

Seems like they missed an opportunity here -- they could have called the combined company the Ornery Renegades... Orna Therapeutics ReNAgade Therapeutics #RNA

CONGRATULATIONS to our newest PhD, Dr. Adam Hedger, co-mentored by Jon Watts and Dr. Celia Schiffer!!!

So proud of the RTI’s fearless leader Phil Zamore ZamoreLabUMass for receiving the The RNA Society & Cold Spring Harbor Laboratory Distinguished Research Mentor Award! CONGRATS 🎉 #RNA24

Ribosomes unexpectedly moonlight as activators of angiogenin enzyme nature.com/articles/d4158…

The RTI & UMass Chan Medical School Medical School seeks the next generation of scientific leaders! Join our research community as a Maraganore Early Independence Fellow. Get 3-5 years of support. Apply by Dec 1 to join us: academicjobsonline.org/ajo/jobs/28425

Hey, senior PhD students working on RNA and moving toward leading independent labs: Apply for the Maraganore Early Independence Fellow program at UMass Chan Medical School RNA Therapeutics Institute and come work with us! linkedin.com/posts/angelame…