New university students have suffered particularly from the measures and restrictions during the #pandemic. #KyriakiKarava and #FlorianHugi, members of our new #Biotechnology Master student cohort report on their experiences at D-​BSSE >bit.ly/3MOzHtf Kyriaki Karava ETH Zurich

Programming diverse neuron subtypes from stem cells! Coupling patterning with proneural TF induction, we screened for 480 morphogen signaling modulations in ~700K cells. Great work with Jasper Janssens Treutlein lab Gray Camp biorxiv.org/content/10.110…

Today in Nature Biotechnology we report on the use of base and prime editing for high throughput interrogation of genetic variants in cancer. Excellent work by first authors Olivier Belli & Kyriaki Karava. 🧵👇 tinyurl.com/2js9dwyp ETH Zurich D-BSSE, ETH Zurich

Researchers at ETH Zurich have combined two #GeneEditing methods. This enables them to quickly investigate the significance of many #GeneticMutations involved in the development and treatment of #Cancer. brnw.ch/21wOzs3

One of the major challenges in human genomics is the functional assessment of variants. Base and prime #CRISPR genome editing is making a big difference for meeting that challenge, as exemplified in this new report Nature Biotechnology nature.com/articles/s4158… Randall Platt

Multimodal scanning of genetic variants with base and prime editing go.nature.com/3O6wQ0O

Exciting research on using #CRISPR to decipher whether gene variants lead to #cancer and advancing base and prime editing tools by Randall Platt ETH Zurich > u.ethz.ch/7ohcV

Combining Base and Prime Editing to Decipher Which Gene Variants Lead to Cancer ETH Zurich researchers combined two CRISPR-Cas methods to decipher how mutations in a cell’s genome affect its function. hubs.li/Q02Y3xbj0

Randall Platt Olivier Belli Kyriaki Karava ETH Zurich D-BSSE, ETH Zurich Basel Research Centre for Child Health Universität Basel @NCCR_MSE Using CRISPR to decipher whether gene variants lead to cancer #NBTintheNews via ETH Zurich ethz.ch/en/news-and-ev…

Randall Platt Olivier Belli Kyriaki Karava ETH Zurich D-BSSE, ETH Zurich Basel Research Centre for Child Health Universität Basel @NCCR_MSE Combining base and prime editing to decipher which gene variants lead to cancer #NBTintheNews via Genetic Engineering & Biotechnology News genengnews.com/topics/cancer/…

And read the News & Views from Francisco J. Sánchez-Rivera highlighting this work, along with related work published in Nature Biotechnology from Randall Platt and colleagues, (nature.com/articles/s4158…), here: nature.com/articles/s4159…

Randall Platt Olivier Belli Kyriaki Karava ETH Zurich D-BSSE, ETH Zurich Basel Research Centre for Child Health Universität Basel @NCCR_MSE Precision mutational scanning: your multipass to the future of genetics - Nature Methods N&V by Francisco J. Sánchez-Rivera nature.com/articles/s4159…

Randall Platt Olivier Belli Kyriaki Karava ETH Zurich D-BSSE, ETH Zurich Basel Research Centre for Child Health Universität Basel @NCCR_MSE Genetic Engineering & Biotechnology News Multimodal editing maps genetic variants in EGFR #NBTintheNews via CRISPR Medicine crisprmedicinenews.com/news/multimoda…