
Kadina Johnston
@kadinaj
ML Protein Engineer | PhD in Bioengineering @Caltech with @francesarnold | proteins, ML, data, methods, and directed evolution (she/her)
ID: 754045662
13-08-2012 00:14:10
103 Tweet
379 Followers
268 Following



Great work by Kadina Johnston and her team--here is a complete enzyme 4-site dataset for #ML4proteins, folks! #enzyme.

Have you ever wondered about how epistasis affects protein engineering efforts? In this case study, we created a combinatorial fitness landscape to explore just that. I am so proud of the work that Kadina Johnston (and everyone else!) put in to make this project a reality. Check it out!

Protein engineers and biochemists (and everyone, really), check out this awesome work by Kadina Johnston constructing a 160,000-member fitness landscape in the active site of (my favorite enzyme!) TrpB. There's one neat result (among many) that I wanted to discuss in more detail: (1/9)