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Is it true that gut-brain signals after consuming ultra-processed foods high in fat+sugar cause exaggerated dopamine release in human brain reward regions akin to what you'd expect from addictive drugs?? The answer may surprise you!!💡🧠 Our latest work from Kevin Hall 's lab!

Drugs like Ozempic are great for weight loss, but they make some people feel sick. We discovered that the brain circuits mediating the appetite suppression are distinct from those that mediate nausea – a finding that may be leveraged to develop more selective GLP1-based drugs.

This dataset indicates a novel fate for ketone bodies (KBs) in PUFA synthesis and biology. While KBs contribute to both DNL and FA elongation, there is a special relationship between KBs and PUFAs that will have both biological and biochemical implications. GREAT teamwork here

Mice are obsessed with palatable high-fat diet, devaluing standard chow even when super hungry. Our latest work shows this is dependent on the amount and type of fat, experience, and post-ingestive feedback thru fat absorption, not taste or smell. gcc02.safelinks.protection.outlook.com/?url=https%3A%…

Unique opportunity to come join us at Pennington Biomedical Research Center with some outstanding mentors - lots of potential for cool science, intellectual growth, and fun along the way 🤓

Thank you, to Dr. Leanne Redman, Dr. Emily Flanagan, and Dr. Kaja Falkenhein of the Reproductive Endocrinology and Women's Health Lab for presenting their work at this week's Work In Progress! #WomenInSTEM #WIP

Tremendous honour to be receiving this award and stand among some of the giants (literally) in the field. Thank you to Dr. Jonathan Little Leanne M. Redman, PhD for the nomination and The Obesity Society for the recognition. UBC School Of Health & Exercise Sciences UBC Okanagan Pennington Biomedical Research Center

Tremendous honour - and I’m excited for what’s to come!

From JL Low et al. (University of British Columbia Dr. Jonathan Little Ali McManus Hashim Islam Kaja Falkenhain) An acute bout of 4 × 4-min or 10 × 1-min HIIT improves β cell glucose sensitivity in postmenopausal females with type 2 diabetes: a secondary analysis 🔗ow.ly/tN4k50UUpI4

Challenging the theory that distinct leptin phenotypes affect energy expenditure or weight change in response to acute or prolonged energy stressors, this one found no association between leptin phenotypes and energy expenditure or weight change.

Check out our new paper looking whether folks having low or high leptin for their fat mass are different in their energetics. Answer - No! Kaja Falkenhain John Speakman Kevin Hall

Thanks for the invitation! Great discussion and nice to reconnect with colleagues

Mobile Health Biometrics to Enhance Exercise and Physical Activity Adherence in Type 2 Diabetes (MOTIVATE-T2D): a decentralised feasibility randomised controlled trial delivered across the UK and Canada bit.ly/41VIO3y

Such a well-deserved honor - we are blessed to witness Leanne M. Redman, PhD's impact and creativity every day here at Pennington Biomedical Research Center!

Ketones (β-hydroxybutyrate) inhibit lipolysis via the HCA2 receptor — but does this feedback loop influence the development of diabetic ketoacidosis? Fascinating study by Maj Bangshaab, Steno Diabetes Center Aarhus Aarhus Universitet Diabetologia #ketone Read more below 👇 link.springer.com/article/10.100…